Evidence map›Paper›PMID 34439068›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Plasma-Activated Saline Promotes Antibiotic Treatment of Systemic Methicillin-Resistant

Lu Yang, Gulimire Niyazi, Yu Qi, Zhiqian Yao, Lingling Huang, Zifeng Wang, Li Guo, Dingxin Liu

Registry-linked trialAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06529159 (H. Pylori Eradication With Argon Plasma During Endoscopy), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06529159 narecruitingnot on this mapstarted 2025, after this paper: background citation

H. Pylori Eradication With Argon Plasma During Endoscopy (HEAPE)

TypeinterventionalSponsorChristopher C. Thompson, MD, MScRan2025 to 2027Enrolled20ConditionsHelicobacter Pylori Infection, Helicobacter Pylori, Helicobacter Pylori Gastrointestinal Tract Infection, H. Pylori InfectionArmsHEAPE, Pre-HEAPE
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Biofilm sensitization to breakJournal of medical microbiology · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Plasma-Activated Water Against Carbapenem-ResistantPathogens (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lu YangSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Gulimire NiyaziSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Yu QiState Key Laboratory of Electrical Insulation and Power Equipment, Center for Plasma Biomedicine, Xi'an Jiaotong University, Xi'an 710049, China.
Zhiqian YaoState Key Laboratory of Electrical Insulation and Power Equipment, Center for Plasma Biomedicine, Xi'an Jiaotong University, Xi'an 710049, China.
Lingling HuangState Key Laboratory of Electrical Insulation and Power Equipment, Center for Plasma Biomedicine, Xi'an Jiaotong University, Xi'an 710049, China.
Zifeng WangState Key Laboratory of Electrical Insulation and Power Equipment, Center for Plasma Biomedicine, Xi'an Jiaotong University, Xi'an 710049, China.
Li GuoState Key Laboratory of Electrical Insulation and Power Equipment, Center for Plasma Biomedicine, Xi'an Jiaotong University, Xi'an 710049, China.
Dingxin LiuState Key Laboratory of Electrical Insulation and Power Equipment, Center for Plasma Biomedicine, Xi'an Jiaotong University, Xi'an 710049, China.

Funding

National Natural Science Foundation of China 51977174
6 · The paper itself

Abstract

Systemic infections caused by methicillin-resistant

Indexed as

biofilmcold atmospheric-pressure plasmamethicillin-resistant Staphylococcus aureusplasma-activated salinesystemic infection

Identifiers

PMID34439068
PMCPMC8388904

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.