Evidence map›Paper›PMID 34439062›Full record

ReviewAntibiotics (Basel, Switzerland)2021

The Revival of Aztreonam in Combination with Avibactam against Metallo-β-Lactamase-Producing Gram-Negatives: A Systematic Review of In Vitro Studies and Clinical Cases.

Carola Mauri, Alberto Enrico Maraolo, Stefano Di Bella, Francesco Luzzaro, Luigi Principe

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Global epidemiology of carbapenem-resistantJAC-antimicrobial resistance · 2026
    Review
  4. Review
  5. Article
  6. Microbiology spectrum · 2026
    Article
  7. In vitro activity of aztreonam-avibactam against carbapenem-resistant Pseudomonas aeruginosa from Southern Brazil.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  8. Microbiology spectrum · 2026
    Article
  9. Article
  10. Antibiotic Choice for Carbapenem-resistantIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  11. Review
  12. Treatment Options for Metallo-Beta-Lactamase-ProducingInternational journal of molecular sciences · 2026
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  18. Review
  19. ComparativeAntimicrobial agents and chemotherapy · 2026
    Article
  20. Article

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carola MauriClinical Microbiology and Virology Unit, "A. Manzoni" Hospital, 23900 Lecco, Italy.
Alberto Enrico MaraoloFirst Division of Infectious Diseases, Cotugno Hospital, AORN dei Colli, 80131 Naples, Italy.ORCID 0000-0002-7218-7762
Stefano Di BellaClinical Department of Medical, Surgical and Health Science, Trieste University, 34128 Trieste, Italy.ORCID 0000-0001-6121-7009
Francesco LuzzaroClinical Microbiology and Virology Unit, "A. Manzoni" Hospital, 23900 Lecco, Italy.ORCID 0000-0002-8275-8389
Luigi PrincipeClinical Pathology and Microbiology Unit, "S. Giovanni di Dio" Hospital, 88900 Crotone, Italy.ORCID 0000-0002-2000-5322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections caused by metallo-β-lactamase (MBL)-producing

Indexed as

antibiotic combinationavibactamaztreonamceftazidime/avibactamEnterobacteraleslast resource antibioticmetallo-β-lactamaseold antibioticPseudomonasStenotrophomonas

Identifiers

PMID34439062
PMCPMC8388901

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.