ReviewAntibiotics (Basel, Switzerland)2021
Polyphenols and Organic Acids as Alternatives to Antimicrobials in Poultry Rearing: A Review.
Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Dietary organic acid supplementation improved productive performance, jejunal morphology, immune status, antioxidant- and inflammation-related gene expression, blood biochemistry, and meat quality of broiler chickens.Veterinary and animal science · 2026Article
- Enhanced Efficacy of Pomegranate Peel Extract via Double Nano-Emulsion Delivery in Laying Hens: Impact on Performance, Immunity, Antioxidant Status, andVeterinary sciences · 2026Article
- Spleen Metabolome Reveals Immune-Mediated Responses Modulated by Onion Peel Extract inMicroorganisms · 2026Article
- Impact of Functional Feed Additives and Lower Antibiotic Use on Poultry Meat Quality and Consumer Perception.Foods (Basel, Switzerland) · 2026Review
- Puerarin modulates the gut-liver-ovarian axis to ameliorate reproductive aging in breeder hens.Microbiome · 2026Article
- Quantum dot butyrate: a novel strategy to improve performance, nutrient digestibility and gut barrier function in broilers.BMC veterinary research · 2026Article
- A chicken-originFrontiers in microbiology · 2026Article
- Rapid Hemi-Synthesis of Multifunctional Amphiphilic Derivatives Based on Polyphenolic Extractives: Surface Activity, Antioxidant and Antibacterial Properties.Molecules (Basel, Switzerland) · 2025Article
- Antibiotics and Opportunities of Their Alternatives in Pig Production: Mechanisms Through Modulating Intestinal Microbiota on Intestinal Health and Growth.Antibiotics (Basel, Switzerland) · 2025Review
- Alternatives to antibiotics for sustainable livestock production in the context of the One Health approach: tackling a common foe.Frontiers in veterinary science · 2025Review
- Cardoon cake as a sustainable alternative ingredient in broiler feeding.Italian journal of animal science · 2025Article
- Article
- Eco-benevolent synthesis of ZnO-NPs and ZnO-MFs from Inula oculus-christi L. (Asteraceae) with effective antioxidant, antimicrobial, DNA cleavage, and decolorization efficiencies.Bioprocess and biosystems engineering · 2024Article
- A Diet Supplemented with Oil-Free Olive Pulp Flour (MOP-ManniOlivePowderAnimals : an open access journal from MDPI · 2024Article
- Influence of Dietary Probiotic and Alpha-Monolaurin on Performance, Egg Quality, Blood Constituents, and Egg Fatty Acids' Profile in Laying Hens.Probiotics and antimicrobial proteins · 2024Article
- Article
- Effect of probiotics and acidifiers on feed intake, egg mass, production performance, and egg yolk chemical composition in late-laying quails.Veterinary world · 2024Article
- Effects of Supplemented Coriander, Ajwain, and Dill Seed Essential Oils on Growth Performance, Carcass Characteristics, Gut Health, Meat Quality, and Immune Status in Broilers.The journal of poultry science · 2024Article
- Article
- Occurrence of Hydroxytyrosol, Tyrosol and Their Metabolites in Italian Cheese.Molecules (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For decades antibiotics have been used in poultry rearing to support high levels of production. Nevertheless, several problems have arisen because of the misuse of antibiotics (i.e., antibiotic resistance, residues in animal products, environmental pollution). Thus, the European Union (EU) as well as the European Food Safety Authority (EFSA) promote action plans to diminish the use of antibiotics in animal production. Alternatives to antibiotics have been studied. Polyphenols (PPs) or organic acids (OAs) seem to be two accredited solutions. Phenolic compounds, such as phenols, flavonoids, and tannins exert their antimicrobial effect with specific mechanisms. In contrast, short chain fatty acids (SCFAs) and medium chain fatty acids (MCFAs), the OAs mainly used as antibiotics alternative, act on the pathogens depending on the pKa value. This review aims to collect the literature reporting the effects of these substances applied as antimicrobial molecules or growth promoter in poultry feeding (both for broilers and laying hens). Organic acids and PPs can be used individually or in blends, exploiting the properties of each component. Collected data highlighted that further research needs to focus on OAs in laying hens' feeding and also determine the right combination in blends with PPs.
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