Evidence map›Paper›PMID 34439031›Full record

ReviewAntibiotics (Basel, Switzerland)2021

Pharmaceutical Approaches on Antimicrobial Resistance: Prospects and Challenges.

Firzan Nainu, Andi Dian Permana, Nana Juniarti Natsir Djide, Qonita Kurnia Anjani, Rifka Nurul Utami, Nur Rahma Rumata, Jianye Zhang, Talha Bin Emran, Jesus Simal-Gandara

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Trial
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  5. Synthesis, characterization, andFrontiers in chemistry · 2026
    Article
  6. Review
  7. One health (Amsterdam, Netherlands) · 2025
    Review
  8. Review
  9. Article
  10. SAAP-148 Oligomerizes into a Hexamer Forming a Hydrophobic Inner Core.Chembiochem : a European journal of chemical biology · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Firzan NainuFaculty of Pharmacy, Hasanuddin University, Makassar 90245, Sulawesi Selatan, Indonesia.ORCID 0000-0003-0989-4023
Andi Dian PermanaFaculty of Pharmacy, Hasanuddin University, Makassar 90245, Sulawesi Selatan, Indonesia.
Nana Juniarti Natsir DjideFaculty of Pharmacy, Hasanuddin University, Makassar 90245, Sulawesi Selatan, Indonesia.
Qonita Kurnia AnjaniFaculty of Pharmacy, Hasanuddin University, Makassar 90245, Sulawesi Selatan, Indonesia.ORCID 0000-0002-4809-550X
Rifka Nurul UtamiFaculty of Pharmacy, Hasanuddin University, Makassar 90245, Sulawesi Selatan, Indonesia.
Nur Rahma RumataFaculty of Pharmacy, Hasanuddin University, Makassar 90245, Sulawesi Selatan, Indonesia.
Jianye ZhangKey Laboratory of Molecular Target & Clinical Pharmacology and the State & NMPA Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, China.ORCID 0000-0001-5242-3687
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID 0000-0003-3188-2272
Jesus Simal-GandaraNutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Food Science and Technology, University of Vigo-Ourense Campus, E32004 Ourense, Spain.ORCID 0000-0001-9215-9737

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid increase in pathogenic microorganisms with antimicrobial resistant profiles has become a significant public health problem globally. The management of this issue using conventional antimicrobial preparations frequently results in an increase in pathogen resistance and a shortage of effective antimicrobials for future use against the same pathogens. In this review, we discuss the emergence of AMR and argue for the importance of addressing this issue by discovering novel synthetic or naturally occurring antibacterial compounds and providing insights into the application of various drug delivery approaches, delivered through numerous routes, in comparison with conventional delivery systems. In addition, we discuss the effectiveness of these delivery systems in different types of infectious diseases associated with antimicrobial resistance. Finally, future considerations in the development of highly effective antimicrobial delivery systems to combat antimicrobial resistance are presented.

Indexed as

antimicrobial resistanceantimicrobialsdrug deliverypharmaceutical preparations

Identifiers

PMID34439031
PMCPMC8388863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.