Evidence map›Paper›PMID 34438975›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Protective Effect of Baicalin against

Abraham Joseph Pellissery, Poonam Gopika Vinayamohan, Deepa Ashwarya Kuttappan, Neha Mishra, Breno de Oliveira Fragomeni, Kendra Maas, Shankumar Mooyottu, Kumar Venkitanarayanan

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biological Mechanisms of Polyphenols againstInfectious disorders drug targets · 2025
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Frontiers in microbiology · 2022
    Article
  6. Introduction to the Special Issue onAntibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abraham Joseph PellisseryDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.
Poonam Gopika VinayamohanDepartment of Veterinary Preventive Medicine, Ohio State University, Columbus, OH 43210, USA.
Deepa Ashwarya KuttappanDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.
Neha MishraDepartment of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA.
Breno de Oliveira FragomeniDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.
Kendra MaasMicrobial Analysis, Resources, and Services, University of Connecticut, Storrs, CT 06269, USA.
Shankumar MooyottuDepartment of Veterinary Pathology, Iowa State University, Ames, IA 50011, USA.
Kumar VenkitanarayananDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.

Funding

Research Excellence Program 2019-2020, Office of Vice President for Research, University of Connecticut https://ovpr.uconn.edu/services/research-development/internal-funding-opportunities/internal-funding-recipients/
6 · The paper itself

Abstract

This study investigated the prophylactic and therapeutic efficacies of baicalin (BC), a plant-derived flavone glycoside, in reducing the severity of

Indexed as

baicalinClostridioides difficilegut dysbiosismicrobiomemouse model

Identifiers

PMID34438975
PMCPMC8388895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.