Evidence map›Paper›PMID 34438971›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Is There a Difference in Microbiological Epidemiology and Effective Empiric Antimicrobial Therapy Comparing Fracture-Related Infection and Periprosthetic Joint Infection? A Retrospective Comparative Study.

Markus Rupp, Susanne Baertl, Nike Walter, Florian Hitzenbichler, Martin Ehrenschwender, Volker Alt

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Clinical epidemiology and case fatality due to antimicrobial resistance in Germany: a systematic review and meta-analysis, 1 January 2010 to 31 December 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Antibiotic-Releasing Porous Shell Cements.Antibiotics (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Markus RuppDepartment for Trauma Surgery, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-7221-3783
Susanne BaertlDepartment for Trauma Surgery, University Medical Center Regensburg, 93053 Regensburg, Germany.
Nike WalterDepartment for Trauma Surgery, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-0654-2076
Florian HitzenbichlerDepartment of Infection Prevention and Infectious Diseases, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0003-4374-2787
Martin EhrenschwenderInstitute of Clinical Microbiology and Hygiene, University Medical Center Regensburg, 93053 Regensburg, Germany.
Volker AltDepartment for Trauma Surgery, University Medical Center Regensburg, 93053 Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate (1) microbial patterns in fracture-related infections (FRIs) in comparison to microbiological patterns of periprosthetic joint infections (PJIs), (2) the identification of effective empiric antibiotic therapy for FRIs and PJIs and (3) analysis of difficult-to-treat (DTT) pathogens. Patients treated for FRIs or PJIs from 2017 to 2020 were evaluated for pathogens detected during treatment. Antibiotic susceptibility profiles were examined with respect to broadly used antibiotics and antibiotic combinations. Resistance rates to rifampicin or fluoroquinolone were determined. A total of 81 patients with PJI and 86 with FRI were included in the study. For FRIs

Indexed as

difficult to treat pathogensempiric antimicrobial therapyfracture-related infectionprosthetic joint infection

Identifiers

PMID34438971
PMCPMC8388716

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.