Evidence map›Paper›PMID 34438948›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Long-Lasting Stable Expression of Human LL-37 Antimicrobial Peptide in Transgenic Barley Plants.

Malihe Mirzaee, Edita Holásková, Alžbeta Mičúchová, David J Kopečný, Zhila Osmani, Ivo Frébort

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Malihe MirzaeeCentre of Region Haná for Biotechnological and Agricultural Research, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, 783 71 Olomouc, Czech Republic.ORCID 0000-0001-6274-7466
Edita HoláskováCentre of Region Haná for Biotechnological and Agricultural Research, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, 783 71 Olomouc, Czech Republic.
Alžbeta MičúchováCentre of Region Haná for Biotechnological and Agricultural Research, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, 783 71 Olomouc, Czech Republic.ORCID 0000-0002-7817-5797
David J KopečnýDepartment of Experimental Biology, Faculty of Science, Palacký University, 783 71 Olomouc, Czech Republic.ORCID 0000-0002-3379-7058
Zhila OsmaniCentre of Region Haná for Biotechnological and Agricultural Research, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, 783 71 Olomouc, Czech Republic.
Ivo FrébortCentre of Region Haná for Biotechnological and Agricultural Research, Czech Advanced Technology and Research Institute (CATRIN), Palacký University, 783 71 Olomouc, Czech Republic.ORCID 0000-0002-4032-4961
Palacký University Olomouc · CZ

Funding

European Regional Development Fund CZ.02.1.01/0.0/0.0/17_048/0007323
6 · The paper itself

Abstract

Antimicrobial peptides play a crucial role in the innate immune system of multicellular organisms. LL-37 is the only known member of the human cathelicidin family. As well as possessing antibacterial properties, it is actively involved in various physiological responses in eukaryotic cells. Accordingly, there is considerable interest in large-scale, low-cost, and microbial endotoxin-free production of LL-37 recombinant peptides for pharmaceutical applications. As a heterologous expression biofactory, we have previously obtained homologous barley (

Indexed as

antimicrobial peptidesbarleyfield-grown progeniesLL-37recombinant protein

Identifiers

PMID34438948
PMCPMC8388648
OpenAlexW3187031911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.