ArticleAnimals : an open access journal from MDPI2021
Assessing the Risk of Nodal Metastases in Canine Integumentary Mast Cell Tumors: Is Sentinel Lymph Node Biopsy Always Necessary?
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Multimodal treatment of canine lower eyelid mast cell tumours: lip-to-lid reconstruction and sentinel lymph node mapping in two cases.BMC veterinary research · 2026Article
- Preputial and scrotal cutaneous mast cell tumors in dogs show no evidence of inherently higher biologic malignancy.Frontiers in veterinary science · 2025Article
- Tumor Grade and Mitotic Count Are Prognostic for Dogs with Cutaneous Mast Cell Tumors Treated with Surgery and Adjuvant or Neoadjuvant Vinblastine Chemotherapy.Veterinary sciences · 2024Article
- The Use of Sentinel Lymph Node Mapping for Canine Mast Cell Tumors.Animals : an open access journal from MDPI · 2024Review
- Intracranial invasion of a mast cell tumour in a dog: A case report and review of the literature.Veterinary medicine and science · 2024Review
- Evaluation of Surgical Aid of Methylene Blue in Addition to Intraoperative Gamma Probe for Sentinel Lymph Node Extirpation in 116 Canine Mast Cell Tumors (2017-2022).Animals : an open access journal from MDPI · 2023Article
- Lymph node metastasis in feline cutaneous low-grade mast cell tumours.Journal of feline medicine and surgery · 2023Article
- Sentinel Lymph Node Mapping and Biopsy in Cats with Solid Malignancies: An Explorative Study.Animals : an open access journal from MDPI · 2022Article
- Sentinel Lymph Node Mapping with Indirect Lymphangiography for Canine Mast Cell Tumour.Veterinary sciences · 2022Article
- The Role of Fine Needle Aspiration of Liver and Spleen in the Staging of Low-Grade Canine Cutaneous Mast Cell Tumor.Veterinary sciences · 2022Article
- Near-infrared fluorescent image-guided lymph node dissection compared with locoregional lymphadenectomies in dogs with mast cell tumours.The Journal of small animal practice · 2022Article
- Sentinel Lymph Node Biopsy Is Feasible in Dogs with Scars from Prior Local Excision of Solid Malignancies.Animals : an open access journal from MDPI · 2022Article
- Plasma small extracellular vesicles from dogs affected by cutaneous mast cell tumors deliver high levels of miR-21-5p.Frontiers in veterinary science · 2022Article
- Proposed Diagnostic Criteria and Classification of Canine Mast Cell Neoplasms: A Consensus Proposal.Frontiers in veterinary science · 2021Review
- Weishaar's classification system for nodal metastasis in sentinel lymph nodes: Clinical outcome in 94 dogs with mast cell tumor.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent literature supports the sentinel lymph node (SLN) biopsy in dogs with MCT due to discrepancy with the regional lymph node and the high percentage of occult metastasis. However, the SLN biopsy includes additional anesthesiologic, diagnostic, and surgical procedures, and additional costs. The study aimed to assess the association between clinicopathological variables and SLN status, determining the identification of dogs at lower risk of SLN metastases. Dogs with integumentary MCT were admitted to the lymphoscintigraphic mapping and subsequent biopsy of SLN. The association between clinicopathological variables of MCT and SLN status was statistically tested, both considering occult and overt metastasis together (HN2-HN3) and overt metastasis (HN3) alone. Fifty low-grade cutaneous MCT and 16 subcutaneous MCT were included. A small to moderate association between integumentary MCT ≥ 3 cm and HN2-HN3 SLN was found. A strong association of integumentary MCT dimension and subcutaneous MCT with HN3 SLN occurred. Dimension of low-grade cutaneous and subcutaneous MCT seems to correlate with SLN status, but additional study should confirm this data before excluding small MCT to the SLN biopsy. On the contrary, the study results induce a solid suggestion for mapping and biopsy of the SLN in MCT > 3 cm and subcutaneous MCT.
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