ArticleAnimals : an open access journal from MDPI2021
Melatonin Promotes In Vitro Maturation of Vitrified-Warmed Mouse Germinal Vesicle Oocytes, Potentially by Reducing Oxidative Stress through the Nrf2 Pathway.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis.International journal of molecular medicine · 2026Article
- Lycopene improves the developmental competence of vitrified-thawed oocytes by reestablishing redox balance and modulating Rock1 expression.Journal of assisted reproduction and genetics · 2025Article
- Melatonin alleviates sodium sulfite-induced osteoporosis in mice via suppression of the ferroptosis pathway.Apoptosis : an international journal on programmed cell death · 2025Article
- Overview of Nrf2 as a target in ovary and ovarian dysfunctions focusing on its antioxidant properties.Journal of ovarian research · 2025Review
- Overcoming ice: cutting-edge materials and advanced strategies for effective cryopreservation of biosample.Journal of nanobiotechnology · 2025Review
- Melatonin decreases excessive polyspermy for single oocyte in pigs through the MT2 receptor.Scientific reports · 2024Article
- The walnut-derived peptide TW-7 improves mouse parthenogenetic embryo development of vitrified MII oocytes potentially by promoting histone lactylation.Journal of animal science and biotechnology · 2024Article
- Ovarian tissue cryopreservation and transplantation: a review on reactive oxygen species generation and antioxidant therapy.Cell and tissue research · 2023Review
- Coping with Oxidative Stress in Reproductive Pathophysiology and Assisted Reproduction: Melatonin as an Emerging Therapeutical Tool.Antioxidants (Basel, Switzerland) · 2022Review
- Review
- Exogenous Melatonin Directly and Indirectly Influences Sheep Oocytes.Frontiers in veterinary science · 2022Article
- The role of melatonin in the development of postmenopausal osteoporosis.Frontiers in pharmacology · 2022Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Previously it was reported that melatonin could mitigate oxidative stress caused by oocyte cryopreservation; however, the underlying molecular mechanisms which cause this remain unclear. The objective was to explore whether melatonin could reduce oxidative stress during in vitro maturation of vitrified-warmed mouse germinal vesicle (GV) oocytes through the Nrf2 signaling pathway or its receptors. During in vitro maturation of vitrified-warmed mouse GV oocytes, there were decreases (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.