Evidence map›Paper›PMID 34438765›Full record

ArticleAnimals : an open access journal from MDPI2021

Effects of Obesity on Adiponectin System Skin Expression in Dogs: A Comparative Study.

Cecilia Dall'Aglio, Margherita Maranesi, Antonio Di Loria, Diego Piantedosi, Paolo Ciaramella, Maria Chiara Alterisio, Elvio Lepri, Francesca Mercati

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cecilia Dall'AglioDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0001-6451-3751
Margherita MaranesiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0002-1727-4118
Antonio Di LoriaDepartment of Veterinary Medicine and Animal Productions, University Federico II of Napoli, Via F. Delpino 1, 080137 Napoli, Italy.
Diego PiantedosiDepartment of Veterinary Medicine and Animal Productions, University Federico II of Napoli, Via F. Delpino 1, 080137 Napoli, Italy.
Paolo CiaramellaDepartment of Veterinary Medicine and Animal Productions, University Federico II of Napoli, Via F. Delpino 1, 080137 Napoli, Italy.ORCID 0000-0002-5518-5378
Maria Chiara AlterisioDepartment of Veterinary Medicine and Animal Productions, University Federico II of Napoli, Via F. Delpino 1, 080137 Napoli, Italy.
Elvio LepriDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0001-8478-8154
Francesca MercatiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0002-8799-1200

Funding

This research was funded by the "Ricerca di Base 2018, Università degli Studi di Perugia" grant assigned to the project "Le adipochine come markers diagnostici nell'obesità: studi clinici e molecolari", scientific coordinator Prof. Francesca Mercati. Ricerca di Base 2018
6 · The paper itself

Abstract

Obesity is an important health issue in dogs since it influences a plethora of associated pathologies, including dermatological disorders. Considering the scarcity of information in pets, this work aimed to evaluate the localization and expression of adiponectin (ADIPOQ) and its two receptors (ADIPOR1 and ADIPOR2) in the skin of 10 obese dogs, compared with serum ADIPOQ level. Through immunohistochemistry, ADIPOQ and ADIPOR2 were observed in the adipose tissue, sweat and sebaceous glands, endothelium, and some connective cells. Both receptors were observed in the epidermis and the hair follicles, other than in the sweat and sebaceous glands. Real-time PCR evidenced that the

Indexed as

ADIPOQADIPOR1ADIPOR2dogimmunohistochemistryintegumentary systemRT-qPCR

Identifiers

PMID34438765
PMCPMC8388499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.