Evidence map›Paper›PMID 34438700›Full record

ArticleAnimals : an open access journal from MDPI2021

Transcriptomic Response under Heat Stress in Chickens Revealed the Regulation of Genes and Alteration of Metabolism to Maintain Homeostasis.

Hana Kim, Hyeran Kim, Pilnam Seong, Devender Arora, Donghyun Shin, Woncheoul Park, Jong-Eun Park

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Suppression rather than activation of the integrated stress response (GCN2-ATF4) pathway extends lifespan in the fly.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hana KimDivision of Animal Genomics and Bioinformatics, National Institute of Animal Science, Wanju 55365, Korea.ORCID 0000-0002-1833-483X
Hyeran KimAnimal Nutrition and Physiology Team, National Institute of Animal Science, Wanju 55365, Korea.
Pilnam SeongAnimal Nutrition and Physiology Team, National Institute of Animal Science, Wanju 55365, Korea.
Devender AroraDivision of Animal Genomics and Bioinformatics, National Institute of Animal Science, Wanju 55365, Korea.ORCID 0000-0003-2207-3668
Donghyun ShinDepartment of Agricultural Convergence Technology, Jeonbuk National University, Jeonju 54896, Korea.
Woncheoul ParkDivision of Animal Genomics and Bioinformatics, National Institute of Animal Science, Wanju 55365, Korea.
Jong-Eun ParkDivision of Animal Genomics and Bioinformatics, National Institute of Animal Science, Wanju 55365, Korea.ORCID 0000-0003-0718-3463

Funding

National Institute of Animal Science PJ01491602
6 · The paper itself

Abstract

Chicken is important livestock that serves as a vital food source which remain largely affected by heat stress. Therefore, we performed the transcriptome analysis to help understand the mechanisms of heat stress response in chickens. In the animal experiments, we grouped them into a normal and severe at 21 and 33 °C, with identified physiologic parameters for 2-weeks. Subsequently, RNA-seq analysis was performed to identify DEGs with a false discovery rate < 0.05 and a fold change ≥ 1.5. In the physiological parameters, we observed average daily gain was declined, rectal temperature and respiration rate was increased in severe group. Among total 245 DEGs, 230 and 15 genes were upregulated and downregulated, respectively. In upregulated DEGs, HSPs,

Indexed as

calcium signaling pathwaychickenheat stressMAPK signaling pathwaytranscriptome analysis

Identifiers

PMID34438700
PMCPMC8388523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.