Evidence map›Paper›PMID 34438693›Full record

ArticleAnimals : an open access journal from MDPI2021

Regulation of Nutritional Metabolism in Transition Dairy Goats: Energy Balance, Liver Activity, and Insulin Resistance in Response to Berberine Supplementation.

Navid Ghavipanje, Mohammad Hasan Fathi Nasri, Seyyed Homayoun Farhangfar, Seyyed Ehsan Ghiasi, Einar Vargas-Bello-Pérez

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  5. Impact of KalanchoeBiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Navid GhavipanjeDepartment of Animal Science, Faculty of Agriculture, University of Birjand, Birjand 97175-331, Iran.ORCID 0000-0001-7819-0527
Mohammad Hasan Fathi NasriDepartment of Animal Science, Faculty of Agriculture, University of Birjand, Birjand 97175-331, Iran.
Seyyed Homayoun FarhangfarDepartment of Animal Science, Faculty of Agriculture, University of Birjand, Birjand 97175-331, Iran.
Seyyed Ehsan GhiasiDepartment of Animal Science, Faculty of Agriculture, University of Birjand, Birjand 97175-331, Iran.
Einar Vargas-Bello-PérezDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Grønnegårdsvej 3, DK-1870 Frederiksberg C, Denmark.ORCID 0000-0001-7105-5752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objectives of this study were to evaluate the alleviating effects of the isoquinoline alkaloid berberine (BBR) on the energy balance (EB), glucose and insulin metabolism, and liver functionality in transition dairy goats, as reflected by blood metabolites and enzymes. Twenty-four primiparous Saanen goats were randomly allocated to four groups. Goats in each group received, ad libitum, the same basal diet during the pre- and post-partum periods of evaluation. Goats received daily0, 1, 2, or 4 g BBR (coded as CON, BBR1, BBR2, and BBR4, respectively). Dry matter intake (DMI) and milk yield were recorded daily. Blood samples were collected on days -21, -14, -7, 0, 7, 14, and 21 relative to kidding, and individual body condition scores (BCSs) were also recorded. Supplementation with either BBR2 or BBR4 increased (

Indexed as

berberineenergy balanceinsulin resistanceliver activitySaanen goatstransition period

Identifiers

PMID34438693
PMCPMC8388389

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.