Evidence map›Paper›PMID 34438664›Full record

ArticleAnimals : an open access journal from MDPI2021

Development of Nanobodies Targeting Peste des Petits Ruminants Virus: The Prospect in Disease Diagnosis and Therapy.

Edson Kinimi, Serge Muyldermans, Cécile Vincke, Steven Odongo, Richard Kock, Satya Parida, Mana Mahapatra, Gerald Misinzo

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Edson KinimiSACIDS Africa Centre of Excellence for Infectious Diseases, SACIDS Foundation for One Health, Sokoine University of Agriculture, P.O. Box 3297, Morogoro 25523, Tanzania.ORCID 0000-0003-2010-6200
Serge MuyldermansLaboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.ORCID 0000-0002-3678-3575
Cécile VinckeLaboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
Steven OdongoDepartment of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity (COVAB), Makerere University, Kampala 7062, Uganda.
Richard KockThe Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield AL9 7TA, UK.ORCID 0000-0002-6561-3209
Satya ParidaSACIDS Africa Centre of Excellence for Infectious Diseases, SACIDS Foundation for One Health, Sokoine University of Agriculture, P.O. Box 3297, Morogoro 25523, Tanzania.ORCID 0000-0001-8253-9461
Mana MahapatraThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.ORCID 0000-0002-3977-1465
Gerald MisinzoSACIDS Africa Centre of Excellence for Infectious Diseases, SACIDS Foundation for One Health, Sokoine University of Agriculture, P.O. Box 3297, Morogoro 25523, Tanzania.ORCID 0000-0003-1827-6403

Funding

EXERCISE IN ELDERLY WITH PERIPHAL VASCULAR DISEASEF32AG005799 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI WOMACK, CHRISTOPHER J · 1997 to 1999
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The Government of the United Republic of Tanzania IDA credit 5799-TZWorld Bank Group WB-ACE II Grant PAD1436
6 · The paper itself

Abstract

Peste des petits ruminants virus (PPRV) causes a highly devastating disease, peste des petits ruminants (PPR) of sheep and goats, that threatens food security, small ruminant production, and the conservation of wild small ruminants in many developing countries, especially in Africa. Robust serological and molecular diagnostic tools are available to detect PPRV infection, but they were mainly developed for domestic sheep and goats. The presence of a wide host range for PPRV does present serological diagnostic challenges. New innovative diagnostic tools are needed to detect PPRV in atypical hosts (e.g.,

Indexed as

alpacacameliddiagnosisheavy-chain only antibodynanobodypeste des petits ruminants virustherapeutics

Identifiers

PMID34438664
PMCPMC8388416

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.