Evidence map›Paper›PMID 34438626›Full record

ArticleAnimals : an open access journal from MDPI2021

Effects of a Maternal Essential Fatty Acid and Conjugated Linoleic Acid Supplementation during Late Pregnancy and Early Lactation on Hematologic and Immunological Traits and the Oxidative and Anti-Oxidative Status in Blood Plasma of Neonatal Calves.

Wendy Liermann, Katrin Lena Uken, Christine Schäff, Laura Vogel, Martina Gnott, Armin Tuchscherer, Erminio Trevisi, Tadeusz Stefaniak, Helga Sauerwein, Arnulf Tröscher and 1 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Prepartum nutrient intake and colostrum yield and composition in ruminants.Animal frontiers : the review magazine of animal agriculture · 2023
    Article
  6. Dietary Oxidized Linoleic Acids Modulate Fatty Acids in Mice.Journal of lipid and atherosclerosis · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wendy LiermannInstitute of Nutritional Physiology "Oskar Kellner", Leibniz Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.ORCID 0000-0002-3172-4074
Katrin Lena UkenInstitute of Nutritional Physiology "Oskar Kellner", Leibniz Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Christine SchäffInstitute of Nutritional Physiology "Oskar Kellner", Leibniz Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Laura VogelInstitute of Nutritional Physiology "Oskar Kellner", Leibniz Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Martina GnottInstitute of Nutritional Physiology "Oskar Kellner", Leibniz Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Armin TuchschererInstitute of Genetics and Biometry, FBN, 18196 Dummerstorf, Germany.
Erminio TrevisiDepartment of Animal Sciences, Food and Nutrition (DIANA), Università Cattolica del Sacro Cuore, 29122 Piacenza, Italy.ORCID 0000-0003-1644-1911
Tadeusz StefaniakDepartment of Immunology, Pathophysiology and Veterinary Preventive Medicine, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, 50-375 Wroclaw, Poland.ORCID 0000-0002-8982-211X
Helga SauerweinInstitute of Animal Science, Physiology and Hygiene Unit, University of Bonn, 53115 Bonn, Germany.ORCID 0000-0002-6905-4053
Arnulf TröscherBASF SE, 68623 Lampertheim, Germany.ORCID 0000-0002-4198-4427
Harald Michael HammonInstitute of Nutritional Physiology "Oskar Kellner", Leibniz Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.ORCID 0000-0001-8698-1257

Funding

BASF no
6 · The paper itself

Abstract

Fatty acids are known for their regulatory role in inflammation and oxidative stress. The present study investigated 38 calves born from dams, abomasally supplemented with coconut oil, essential fatty acids (EFA), conjugated linoleic acid (CLA) or EFA + CLA, according to immunological traits and the oxidative and anti-oxidative status for the first 5 days of life. On day 2 of life, plasma total bilirubin, cholesterol, interleukin 1-β and ferric ion reducing anti-oxygen power (FRAP) were lower in calves with than without maternal EFA supplementation, and FRAP additionally on day 4. On day 3, the concentrations of reactive oxygen metabolites were higher in calves with than without maternal EFA supplementation and additionally on day 5 together of retinol. Total leucocyte counts were decreased in the EFA group compared to the CLA group on day 5. Lymphocyte proportions decreased from day 1 to 5 only in the EFA + CLA group. On day 2, plasma total protein was higher in CLA and EFA + CLA than in EFA calves. Similarly, CLA calves had higher interleukin 1-β concentrations compared to EFA + CLA calves. FRAP was decreased by CLA on day 4. Overall, the maternal fatty acid supply affected the inflammatory response and the oxidative and anti-oxidative status of the neonatal offspring.

Indexed as

anti-oxidantsbilirubincalfconjugated linoleic acidessential fatty acidinflammation

Identifiers

PMID34438626
PMCPMC8388434

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.