Evidence map›Paper›PMID 34438553›Full record

ArticleChildren (Basel, Switzerland)2021

Parental Stress and Scalp Hair Cortisol in Excessively Crying Infants: A Case Control Study.

Ineke de Kruijff, Ellen Tromp, Mijke P Lambregtse-van den Berg, Arine M Vlieger, Marc A Benninga, Yolanda B de Rijke, Erica Lt van den Akker

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ineke de KruijffDepartment of Pediatrics, St Antonius Hospital Nieuwegein, 3435 CM Nieuwegein, The Netherlands.
Ellen TrompDepartment of Epidemiology and Statistics, St Antonius Hospital Nieuwegein, 3435 CM Nieuwegein, The Netherlands.
Mijke P Lambregtse-van den BergDepartments of Psychiatry and Child and Adolescent Psychiatry, Erasmus MC, 3000 CA Rotterdam, The Netherlands.ORCID 0000-0003-1764-5940
Arine M VliegerDepartment of Pediatrics, St Antonius Hospital Nieuwegein, 3435 CM Nieuwegein, The Netherlands.
Marc A BenningaDepartment of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Yolanda B de RijkeDepartment of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Erica Lt van den AkkerDepartment of Pediatrics, Pediatric Endocrinology, Erasmus MC, University Medical Center Rotterdam, Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.ORCID 0000-0001-5352-9328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaring for an excessively crying infant (ECI) can be stressful for mothers and fathers and is associated with mental and bonding problems. Hair cortisol offers a unique measure for the biological reaction of the body to stress over time.

methodsIn this case-control study, scalp hair cortisol concentrations (HCC) were measured using liquid chromatography-tandem mass spectrometry (LC-MS) in 35 mothers and 23 fathers and their ECIs. The control group consisted of 64 mothers and 63 fathers of non-ECIs of similar age. Parental stress, depression, anxiety and bonding were assessed using validated questionnaires.

resultsMean HCC were significantly lower in mothers and fathers of ECIs (2.3 pg/mg, 95% CI 1.8-2.9 and 1.6 pg/mg, 95% CI 1.3-2.0) than that in control mothers and fathers (3.2 pg/mg, 95% CI 3.0-3.7 and 2.9 pg/mg, 95% CI 2.5-3.5). In the total group of parents and within the parents of ECIs, HCC were not associated with negative feelings. In the control group, HCC showed a positive association with stress and depression (r = 0.207,

conclusionParents of ECIs showed significantly lower HCC than control parents, reflecting a diminished response of the hypothalamic-pituitary-adrenal (HPA) axis. More research is needed to examine whether this decrease in response is pre-existing or caused by excessive infant crying.

Indexed as

excessive cryingfatherhair cortisolinfantinfant colicmotherstress

Identifiers

PMID34438553
PMCPMC8391563

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