Evidence map›Paper›PMID 34438540›Full record

ReviewChildren (Basel, Switzerland)2021

Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management.

Jozef Klučka, Eva Klabusayová, Tereza Musilová, Tereza Kramplová, Tamara Skříšovská, Milan Kratochvíl, Martina Kosinová, Ondřej Horák, Hana Ošlejšková, Petr Jabandžiev and 1 more

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jozef KlučkaDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Eva KlabusayováDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.ORCID 0000-0002-5073-9415
Tereza MusilováDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Tereza KramplováDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Tamara SkříšovskáDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Milan KratochvílDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Martina KosinováDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.ORCID 0000-0002-2982-8974
Ondřej HorákDepartment of Paediatric Neurology, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Hana OšlejškováDepartment of Paediatric Neurology, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Petr JabandžievDepartment of Paediatrics, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.ORCID 0000-0002-4094-2364
Petr ŠtouračDepartment of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.ORCID 0000-0003-1944-5926

Funding

Ministerstvo Školství, Mládeže a Tělovýchovy MUNI/A/1153/2020Ministerstvo Školství, Mládeže a Tělovýchovy MUNI/A/1178/2020Ministerstvo Zdravotnictví Ceské Republiky FNBr, 65269705
6 · The paper itself

Abstract

Acute Ischemic Stroke (AIS) in children is an acute neurologic emergency associated with significant morbidity and mortality. Although the incidence of AIS in pediatric patients is considerably lower than in adults, the overall cumulative negative impact of the quality of life could be even higher in children. The age-related variable clinical presentation could result in a delay in diagnosis and could negatively influence the overall outcome. The early management should be based on early recognition, acute transfer to pediatric AIS centre, standardised approach (ABCDE), early neurologic examination together with neuroimaging (preferable Magnetic Resonance Imaging-MRI). The treatment is based on supportive therapy (normoxemia, normocapnia, normotension and normoglycemia) in combination with intravenous/intraarterial thrombolytic therapy and/or mechanical thrombectomy in selected cases. Pediatric stroke centres, together with the implementation of local stroke management protocols, could further improve the outcome of pediatric patients with AIS.

Indexed as

childinitial approachischemic strokemanagementpediatric

Identifiers

PMID34438540
PMCPMC8394345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.