ReviewChildren (Basel, Switzerland)2021
Pulmonary Vein Stenosis-Evolving Surgical Management of a Challenging Disease.
Review in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Imatinib Mesylate and Sirolimus Inhibit Vascular Fibroproliferative Remodeling in Pulmonary Vein Stenosis.Children (Basel, Switzerland) · 2026Article
- A translational framework for patient-specific modeling of pulmonary vein stenosis.JTCVS open · 2026Article
- Impact of Structured Surveillance and Intervention on Long-Term Vein Outcomes in Pediatric Pulmonary Vein Stenosis.Children (Basel, Switzerland) · 2026Article
- Hiding in Plain Sight: Pulmonary Vein Stenosis Following Pediatric Heart Transplantation.Pediatric transplantation · 2025Review
- Insights into the molecular mechanism of pulmonary vein stenosis in pediatric patients with congenital heart disease.JTCVS open · 2025Article
- Prevalence and Clinical Implications of Pulmonary Vein Stenosis in Bronchiectasis: A 3D Reconstruction CT Study.Advances in respiratory medicine · 2024Article
- Patient-specific 3DFrontiers in cardiovascular medicine · 2024Article
- Absorbable metal stents for vascular use in pediatric cardiology: progress and outlook.Frontiers in cardiovascular medicine · 2024Review
- A neonatal rat model of pulmonary vein stenosis.Cell & bioscience · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary vein stenosis (PVS) is an extremely challenging clinical problem in congenital heart disease. It has traditionally required multimodal therapy given its complex underlying pathophysiology. As with other modalities, surgical therapy has undergone tremendous evolution since the 1950s. These evolving strategies have been based upon an improved understanding of the substrates that cause PVS and recurrent vein obstruction. More recent anatomic-based surgical strategies have focused on the pulmonary vein course, and how adjacent mediastinal structures can create a fulcrum effect on the pulmonary veins as they pass from the lung parenchyma to the left atrium. The consequent angulation of pulmonary veins creates altered wall shear stress and likely serves as a nidus for recurrent PVS. Encouraging early results suggest that eliminating pulmonary vein angulation and shortening/straightening the pulmonary vein course may prove effective in surgically managing PVS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.