Evidence map›Paper›PMID 34438506›Full record

ArticleChildren (Basel, Switzerland)2021

Specialized Pediatric Palliative Care Services in Pediatric Hematopoietic Stem Cell Transplant Centers.

Hilda Mekelenkamp, Teija Schröder, Eugenia Trigoso, Daphna Hutt, Jacques-Emmanuel Galimard, Anne Kozijn, Arnaud Dalissier, Marjola Gjergji, Sarah Liptrott, Michelle Kenyon and 5 more

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Palliative Care for Childhood Cancer.Children (Basel, Switzerland) · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hilda MekelenkampWillem-Alexander Children's Hospital, Department of Pediatrics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-4410-1845
Teija SchröderNew Children's Hospital, P.O. Box 347, 00029 Helsinki, Finland.
Eugenia TrigosoPaediatric Transplant Unit, Hospital University and Polytechnic Hospital LA FE, Avinguda de Fernando Abril Martorell, 106, 46026 Valencia, Spain.
Daphna HuttDivision of Pediatric Hematology and Oncology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan 52621, Israel.ORCID 0000-0003-4354-5193
Jacques-Emmanuel GalimardEBMT Statistical Unit, CEDEX 12, 75571 Paris, France.ORCID 0000-0001-9102-4427
Anne KozijnEBMT Leiden Study Unit, Rijnsburgerweg 10, 2333 AA Leiden, The Netherlands.
Arnaud DalissierEBMT Paris Study Unit, CEDEX 12, 75571 Paris, France.
Marjola GjergjiOspedale Pediatrico Bambino Gesù, Department of Onco-Hematology and Cell and Gene Therapy, Piazza di Sant'Onofrio, 4, 00165 Rome, Italy.
Sarah LiptrottIEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Michelle KenyonDepartment of Haematological Medicine, King's College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK.
John MurrayHaematology and Transplant Unit, Christie Hospital NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
Selim CorbaciogluDepartment of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93052 Regensburg, Germany.
Peter BaderDivision for Stem Cell Transplantation, Immunology and Intensive Care Medicine, Department for Children and Adolescents, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.ORCID 0000-0003-4554-0265
On Behalf Of The Ebmt-Nurses Group
Paediatric Diseases Working Party

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic stem cell transplantation (HSCT) is widely used in pediatric patients as a successful curative therapy for life-threatening conditions. The treatment is intensive, with risks of serious complications and lethal outcomes. This study aimed to provide insight into current data on the place and cause of death of transplanted children, the available specialized pediatric palliative care services (SPPCS), and what services HSCT professionals feel the SPPCS team should provide. First, a retrospective database analysis on the place and cause of death of transplanted pediatric HSCT patients was performed. Second, a survey was performed addressing the availability of and views on SPPCS among HSCT professionals. Database analysis included 233 patients of whom the majority died in-hospital: 38% in the pediatric intensive care unit, 20% in HSCT units, 17% in other hospitals, and 14% at home or in a hospice (11% unknown). For the survey, 98 HSCT professionals from 54 centers participated. Nearly all professionals indicated that HSCT patients should have access to SPPCS, especially for pain management, but less than half routinely referred to this service at an early stage. We, therefore, advise HSCT teams to integrate advance care planning for pediatric HSCT patients actively, ideally from diagnosis, to ensure timely SPPCS involvement and maximize end-of-life preparation.

Indexed as

hematopoietic stem cell transplantationpalliative carepalliative care servicespediatric

Identifiers

PMID34438506
PMCPMC8393700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.