Evidence map›Paper›PMID 34437630›Full record

ArticlePloS one2021

Multiple states in ongoing neural activity in the rat visual cortex.

Daichi Konno, Shinji Nishimoto, Takafumi Suzuki, Yuji Ikegaya, Nobuyoshi Matsumoto

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daichi KonnoGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Shinji NishimotoCenter for Information and Neural Networks, National Institute of Information and Communications Technology, Suita City, Osaka, Japan.
Takafumi SuzukiCenter for Information and Neural Networks, National Institute of Information and Communications Technology, Suita City, Osaka, Japan.
Yuji IkegayaGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Nobuyoshi MatsumotoGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-0426-9416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain continuously produces internal activity in the absence of afferently salient sensory input. Spontaneous neural activity is intrinsically defined by circuit structures and associated with the mode of information processing and behavioral responses. However, the spatiotemporal dynamics of spontaneous activity in the visual cortices of behaving animals remain almost elusive. Using a custom-made electrode array, we recorded 32-site electrocorticograms in the primary and secondary visual cortex of freely behaving rats and determined the propagation patterns of spontaneous neural activity. Nonlinear dimensionality reduction and unsupervised clustering revealed multiple discrete states of the activity patterns. The activity remained stable in one state and suddenly jumped to another state. The diversity and dynamics of the internally switching cortical states would imply flexibility of neural responses to various external inputs.

Indexed as

AnimalsElectrocorticographyElectrodesMaleNeuronsRatsRats, Long-EvansVisual Cortex

Identifiers

PMID34437630
PMCPMC8389421

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.