Evidence map›Paper›PMID 34437616›Full record

ArticlePloS one2021

Alcohol use during pregnancy in Rakai, Uganda.

Adriane Wynn, Dorean Nabukalu, Tom Lutalo, Maria Wawer, Larry W Chang, Susan M Kiene, David M Serwadda, Nelson Sewankambo, Fred Nalugoda, Godfrey Kigozi and 1 more

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adriane WynnDivision of Infectious Diseases & Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, CA, United States of America.ORCID 0000-0001-8067-3616
Dorean NabukaluRakai Health Sciences Program/Uganda Virus Research Institute, Kalisizo, Uganda.ORCID 0000-0002-2680-0669
Tom LutaloRakai Health Sciences Program/Uganda Virus Research Institute, Kalisizo, Uganda.
Maria WawerRakai Health Sciences Program/Uganda Virus Research Institute, Kalisizo, Uganda.
Larry W ChangRakai Health Sciences Program/Uganda Virus Research Institute, Kalisizo, Uganda.
Susan M KieneDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, CA, United States of America.
David M SerwaddaMakerere University School of Public Health, Kampala, Uganda.
Nelson SewankamboMakerere University School of Medicine, Kampala, Uganda.
Fred NalugodaRakai Health Sciences Program/Uganda Virus Research Institute, Kalisizo, Uganda.
Godfrey KigoziRakai Health Sciences Program/Uganda Virus Research Institute, Kalisizo, Uganda.
Jennifer A WagmanDepartment of Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles, CA, United States of America.

Funding

Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Modeling reductions in harmful alcohol use on HIV transmission and mortality in the era of universal test and treat in UgandaK01AA027733 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WYNN, ADRIANE MICHELLE · 2020 to 2024
$888k
NIAAA NIH HHS K01 AA027733NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

introductionAntenatal alcohol use is linked to adverse maternal and neonatal outcomes. Uganda has one of the highest rates of alcohol use in sub-Saharan Africa, but the prevalence of antenatal alcohol use has not been reported in the Rakai region.

methodsWe used cross-sectional data from pregnant women in the Rakai Community Cohort Study between March 2017 and September 2018. Using bivariate and multivariable analyses, we assessed associations between self-reported antenatal alcohol use and sociodemographic characteristics, intimate partner violence (IPV), and HIV status.

resultsAmong 960 pregnant women, the median age was 26 years, 35% experienced IPV in the past 12 months, 13% were living with HIV, and 33% reported alcohol use during their current pregnancy. After adjusting for marital status, education, smoking, and HIV status; Catholic religion (AOR: 3.54; 95% CI: 1.89-6.64; compared to other), bar/restaurant work (AOR: 2.40; 95% CI: 1.17-4.92; compared to agriculture), >one sex partner in past year (AOR: 1.92; 95% CI: 1.17-3.16), a partner that drank before sex in past year (AOR: 2.01; 95% CI: 1.48-2.74), and past year IPV (AOR: 1.55; 95% CI: 1.14-2.11) were associated with antenatal alcohol use.

conclusionWe found that alcohol use during pregnancy was common and associated with religion, occupation, higher numbers of past year sex partners, having a partner who drank before sex in the past 12 months, and IPV experience. More research is needed to understand the quantity, frequency, and timing of antenatal alcohol use; and potential impacts on neonates; and to identify services that are acceptable and effective among pregnant women.

Indexed as

AdolescentAdultAlcohol DrinkingCohort StudiesFemaleHumansIntimate Partner ViolenceLogistic ModelsPregnancyUgandaYoung Adult

Identifiers

PMID34437616
PMCPMC8389483

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.