ArticlePloS one2021
The impact of chronic comorbidities at the time of breast cancer diagnosis on quality of life, and emotional health following treatment in Canada.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Racial Differences in Symptom Burden and Endocrine Therapy Adherence in Breast Cancer: A Post Hoc Analysis of a Randomized Trial.Journal of the National Comprehensive Cancer Network : JNCCN · 2025Trial
- Health-Related Quality of Life in Breast Cancer Patients Undergoing Chemotherapy: A Cross-Sectional Study in Greece.Medicina (Kaunas, Lithuania) · 2026Article
- Observational
- Impact of Pre-Diagnosed Depressive Symptoms on Treatment Choice, Delay in Initiating Treatment, and Mortality Among Women Aged ≥65 Years with Breast Cancer.International journal of environmental research and public health · 2026Article
- Robust Association of Breast Cancer Co-morbidity Using Subtype-specific Expressed Genes.Current drug targets · 2026Article
- Lifestyle Factors and Family History of Diabetes as Significant Risks for Breast Cancer: A Hospital-Based Cohort Study in Tamil Nadu, India.Indian journal of surgical oncology · 2025Article
- Attitudes toward AI-generated risk prediction in patients with early breast cancer: an international multicenter survey.Acta oncologica (Stockholm, Sweden) · 2025Article
- Caregiving responsibility and psychological distress among community-dwelling cancer survivors in the United States.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Patient-Reported Outcomes in Geriatric Oncology-Balancing Quality of Life and Therapeutic Effectiveness Using Primary Breast Cancer as a Model.Drugs & aging · 2025Review
- Article
- Correlates of health-related quality of life in African Americans diagnosed with cancer: a review of survivorship studies and the Detroit research on cancer survivors cohort.Cancer metastasis reviews · 2024Review
- Impact of type 2 diabetes on complications after primary breast cancer surgery: Danish population-based cohort study.The British journal of surgery · 2024Article
- Impact of Patient Comorbidities on Presentation Stage of Breast and Colon Cancers.Annals of surgical oncology · 2023Article
- Presence of Multi-Morbidities and Colorectal Cancer Screening Utilization among Breast Cancer Survivors.Cancers · 2023Article
- Case Report: Intraoperative radiotherapy as the new standard of care for breast cancer patients with disabling health conditions or impairments.Frontiers in oncology · 2023Article
- The association between comorbidities and stigma among breast cancer survivors.Scientific reports · 2022Article
- Multidisciplinary approach to treatment with immune checkpoint inhibitors in patients with HIV, tuberculosis, or underlying autoimmune diseases.Frontiers in medicine · 2022Review
- Understanding the Quality of Life Among Patients With Cancer in Saudi Arabia: Insights From a Cross-Sectional Study.Cancer control : journal of the Moffitt Cancer CenterArticle
- Multimorbidity and Its Associations With Anxiety and Depression Among Newly Diagnosed Patients With Breast Cancer: A Retrospective Observational Cohort Study in a US Commercially Insured and Medicare Advantage Population.Cancer control : journal of the Moffitt Cancer CenterObservational
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
introductionAdvances in breast cancer screening and treatment have led to an increasing number of breast cancer survivors. The objective of this study was to determine the impact of comorbidities on self-reported quality of life (QOL) and emotional health following a breast cancer diagnosis and treatment.
methodsWomen with a personal history of breast cancer (N = 3,372) were identified from the cross-sectional Canadian Partnership Against Cancer (CPAC) Experiences of Cancer Patients in Transitions Survey. Multinomial (nominal) logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for the relationship between burden of comorbidities and overall QOL and emotional health (very poor/poor, fair, good, very good).
resultsOf the 3,372 participants, 57% reported at least one chronic condition at the time of breast cancer diagnosis. As the number of chronic conditions at diagnosis increased, the odds of reporting worse quality of life and emotional health following treatment also increased. Specifically, compared to women reporting very good QOL, for each additional chronic condition, women reported significantly higher odds of reporting good (OR = 1.22, 95% CI: 1.12, 1.32), fair (OR = 1.76, 95% CI: 1.58, 1.96), or poor/very poor (OR = 2.31, 95% CI: 1.86, 2.88) QOL. Similarly, for each additional comorbidity, women reported significantly higher odds of reporting good (OR = 1.17, 95% CI: 1.07, 1.28), fair (OR = 1.63, 95% CI: 1.46, 1.82), or poor/very poor (OR = 2.17, 95% CI: 1.81, 2.60) emotional health, relative to very good emotional health.
conclusionBreast cancer survivors coping with a high comorbidity burden experience worse overall QOL and emotional health following treatment. This highlights the importance of integrating information on comorbidities into survivorship care to improve the experience and overall outcomes of patients with complex needs.
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