Evidence map›Paper›PMID 34437297›Full record

ArticleJournal of behavioral addictions2021

Aberrant orbitofrontal cortex reactivity to erotic cues in Compulsive Sexual Behavior Disorder.

Karolina Golec, Małgorzata Draps, Rudolf Stark, Agnieszka Pluta, Mateusz Gola

Open access · goldAbstract read
In one paragraph

Article in Journal of behavioral addictions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  14. Separating desire from prediction of outcome value.Trends in cognitive sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Karolina Golec1 Faculty of Psychology, University of Warsaw, Warsaw, Poland.ORCID 0000-0002-4651-685X
Małgorzata Draps2 Institute of Psychology, Polish Academy of Sciences, Warsaw, Poland.
Rudolf Stark3 Department of Psychotherapy and Systems Neuroscience, Justus Liebig University of Giessen, Giessen, Germany.
Agnieszka Pluta1 Faculty of Psychology, University of Warsaw, Warsaw, Poland.
Mateusz Gola2 Institute of Psychology, Polish Academy of Sciences, Warsaw, Poland.
University of Warsaw · PLInstitute of Psychology · PLJustus-Liebig-Universität Gießen · DEUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsCompulsive Sexual Behavior Disorder (CSBD) is characterized by increased reactivity to erotic reward cues. Cue-encoded reward parameters, such as type (e.g. erotic or monetary) or probability of anticipated reward, shape reward-related motivational processes, increase the attractiveness of cues and therefore might enhance maladaptive behavioral patterns in CSBD. Studies on the neural patterns of cue processing in individuals with CSBD have been limited mainly to ventral striatal responses. Therefore, here we aimed to examine the cue reactivity of multiple key structures in the brain's reward system, taking into account not only the type of predicted reward but also its probability.

methodsTwenty Nine men seeking professional help due to CSBD and 24 healthy volunteers took part in an fMRI study with a modified Incentive Delay Task with erotic and monetary rewards preceded by cues indicating a 25%, 50%, or 75% chance of reward. Analyses of functional patterns of activity related to cue type and probability were conducted on the whole-brain and ROI levels.

resultsIncreased anticipatory response to cues predictive of erotic rewards was observed among CSBD participants when compared to controls, in the ventral striatum and anterior orbitofrontal cortex (aOFC). The activity in aOFC was modulated by reward probability. DISCUSSION AND

conclusionsType of anticipated reward (erotic vs monetary) affects reward-related behavioral motivation in CSBD more strongly than reward probability. We present evidence of abnormal aOFC function in CSBD by demonstrating the recruitment of additional subsections of this region by erotic reward cues.

Indexed as

CuesEroticaCompulsive BehaviorHumansMagnetic Resonance ImagingMaleMotivationPrefrontal CortexRewardSexual Behaviorcompulsive Sexual Behavior Disordererotic stimulifMRIincentive salience

Identifiers

PMID34437297
PMCPMC8997235
OpenAlexW3194222676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.