ArticleScience (New York, N.Y.)2021
Retinal waves prime visual motion detection by simulating future optic flow.
Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 94 citations in OpenAlex.
- Distinct cortical spatial representations learned along disparate visual pathways.Science advances · 2026Article
- A single computational objective can produce specialization of streams in visual cortex.Nature communications · 2026Article
- Retinal waves shape starburst amacrine cell dendrite development through a direction-selective dendritic computation.Cell reports · 2026Article
- Article
- Long-range axon branching: contributions to brain network plasticity and repair.Nature reviews. Neuroscience · 2026Review
- Mouse model of Angelman syndrome exhibits reduced retinal activity during development.Frontiers in neuroscience · 2026Article
- A toolbox for navigating and analyzing the spatiotemporal properties of retinal waves.bioRxiv : the preprint server for biology · 2025Article
- Four neurons pattern brain-wide developmental activity through neuropeptide signaling.bioRxiv : the preprint server for biology · 2025Article
- A Critical Look at Critical Periods.Annual review of vision science · 2025Review
- Activity-dependent development of synaptic circuits mediates direction selectivity in an axis-specific manner.Cell reports · 2025Article
- High-density Multielectrode Array Recordings of Retinal Waves Using An Electrophysiology Platform.Journal of visualized experiments : JoVE · 2025Article
- Stereotyped Spatiotemporal Dynamics of Spontaneous Activity in Visual Cortex Prior to Eye Opening.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neural waves and computation in a neural net model III: preplay, working memory and bursts.Journal of computational neuroscience · 2025Article
- Three systems of circuit formation: assembly, updating and tuning.Nature reviews. Neuroscience · 2025Review
- Broken time-reversal symmetry in visual motion detection.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Retinal ganglion cell circuits and glial interactions in humans and mice.Trends in neurosciences · 2024Review
- Distinct codes for environment structure and symmetry in postrhinal and retrosplenial cortices.Nature communications · 2024Article
- Hebbian instruction of axonal connectivity by endogenous correlated spontaneous activity.Science (New York, N.Y.) · 2024Article
- A unifying framework for functional organization in early and higher ventral visual cortex.Neuron · 2024Article
- Priming central sound processing circuits through induction of spontaneous activity in the cochlea before hearing onset.Trends in neurosciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The ability to perceive and respond to environmental stimuli emerges in the absence of sensory experience. Spontaneous retinal activity prior to eye opening guides the refinement of retinotopy and eye-specific segregation in mammals, but its role in the development of higher-order visual response properties remains unclear. Here, we describe a transient window in neonatal mouse development during which the spatial propagation of spontaneous retinal waves resembles the optic flow pattern generated by forward self-motion. We show that wave directionality requires the same circuit components that form the adult direction-selective retinal circuit and that chronic disruption of wave directionality alters the development of direction-selective responses of superior colliculus neurons. These data demonstrate how the developing visual system patterns spontaneous activity to simulate ethologically relevant features of the external world and thereby instruct self-organization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.