Evidence map›Paper›PMID 34436901›Full record

ArticleJournal of proteome research2021

Integrated Phosphoproteomics for Identifying Substrates of Human Protein Kinase A (

Adak Karamafrooz, Jack Brennan, David D Thomas, Laurie L Parker

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Adak KaramafroozDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Jack BrennanIndependent Technology Consultant, LIC, Boston, Massachusetts 02129, United States.
David D ThomasDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-8822-2040
Laurie L ParkerDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-6234-3346
University of Minnesota · US

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Vittorio Sebastiano · 2007 to 2026
$71.4M
Biosensor Assay to Screen for Signaling Pathway Inhibition in CancerR01CA182543 · NCI · UNIVERSITY OF MINNESOTA · PI PARKER, LAURIE L. · 2014 to 2018
$2.1M
Mechanistic and Biomarker Studies on Cancer Progression and Taxane ResistanceF31CA183571 · NCI · YALE UNIVERSITY · PI MOORE, LAUREN MICHELLE · 2013 to 2016
$108k
NCI NIH HHS F31 CA183571NCI NIH HHS P30 CA124435NCI NIH HHS R01 CA182543
6 · The paper itself

Abstract

The

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAdolescentCyclic AMP-Dependent Protein Kinase Catalytic SubunitsGene Expression Regulation, NeoplasticHSP40 Heat-Shock ProteinsHumansOncogenesCyclic AMP-Dependent Protein Kinase Catalytic SubunitsDNAJB1 protein, humanHSP40 Heat-Shock ProteinsPRKACA protein, humanDNAJB1−PRKACAfibrolamellar hepatocellular carcinomaFL-HCCkinase inhibitorskinase−substrate identificationphosphoproteomicsPKAprotein kinase A

Identifiers

PMID34436901
PMCPMC10153428
OpenAlexW3194482375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.