ArticleAnnals of intensive care2021
Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU: results from the international A- TEAMICU survey.
Article in Annals of intensive care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Pooled it
- Article
- [Quality of early sepsis diagnostics in German intensive care units-Results of a nationwide survey].Die Anaesthesiologie · 2025Article
- Editorial: The impact of pharmacokinetics and pharmacodynamics on antimicrobial stewardship.Frontiers in cellular and infection microbiology · 2025Article
- Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam inAntimicrobial agents and chemotherapy · 2024Article
- When to Stop Antibiotics in the Critically Ill?Antibiotics (Basel, Switzerland) · 2024Review
- Factors Influencing Integration and Usability of Model-Informed Precision Dosing Software in the Intensive Care Unit.Applied clinical informatics · 2024Article
- Antimicrobial Stewardship in the Hospital Setting: A Narrative Review.Antibiotics (Basel, Switzerland) · 2023Review
- Method Development for Determination of Doripenem in Human Plasma via Capillary Electrophoresis Coupled with Field-Enhanced Sample Stacking and Sweeping.International journal of molecular sciences · 2023Article
- Preventing Multidrug-Resistant Bacterial Transmission in the Intensive Care Unit with a Comprehensive Approach: A Policymaking Manual.Antibiotics (Basel, Switzerland) · 2023Review
- What's new in therapeutic drug monitoring of antimicrobials?Intensive care medicine · 2023Article
- International survey of antibiotic dosing and monitoring in adult intensive care units.Critical care (London, England) · 2023Article
- Antibiotic stewardship in the ICU: time to shift into overdrive.Annals of intensive care · 2023Review
- Optimization of Therapy and the Risk of Probiotic Use during Antibiotherapy in Septic Critically Ill Patients: A Narrative Review.Medicina (Kaunas, Lithuania) · 2023Review
- Chinese consensus guidelines for therapeutic drug monitoring of polymyxin B, endorsed by the Infection and Chemotherapy Committee of the Shanghai Medical Association and the Therapeutic Drug Monitoring Committee of the Chinese Pharmacological Society.Journal of Zhejiang University. Science. B · 2023Article
- Therapeutic Drug Monitoring of Amikacin in Neutropenic Oncology Patients.Antibiotics (Basel, Switzerland) · 2023Article
- Pharmacokinetic Alterations Associated with Critical Illness.Clinical pharmacokinetics · 2023Review
- Planning and development of an antimicrobial stewardship program in penitentiary facilities: strategies to optimize therapeutic prescribing and reduce the incidence of antibiotic resistance.Frontiers in public health · 2023Article
- Review
- Therapeutic drug monitoring practices of anti-infectives: An Asia-wide cross-sectional survey.Frontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
10 authors at 9 institutions in 5 countries.
Funding
Abstract
backgroundSevere infections and multidrug-resistant pathogens are common in critically ill patients. Antimicrobial stewardship (AMS) and therapeutic drug monitoring (TDM) are contemporary tools to optimize the use of antimicrobials. The A-TEAMICU survey was initiated to gain contemporary insights into dissemination and structure of AMS programs and TDM practices in intensive care units.
methodsThis study involved online survey of members of ESICM and six national professional intensive care societies.
resultsData of 812 respondents from mostly European high- and middle-income countries were available for analysis. 63% had AMS rounds available in their ICU, where 78% performed rounds weekly or more often. While 82% had local guidelines for treatment of infections, only 70% had cumulative antimicrobial susceptibility reports and 56% monitored the quantity of antimicrobials administered. A restriction of antimicrobials was reported by 62%. TDM of antimicrobial agents was used in 61% of ICUs, mostly glycopeptides (89%), aminoglycosides (77%), carbapenems (32%), penicillins (30%), azole antifungals (27%), cephalosporins (17%), and linezolid (16%). 76% of respondents used prolonged/continuous infusion of antimicrobials. The availability of an AMS had a significant association with the use of TDM.
conclusionsMany respondents of the survey have AMS in their ICUs. TDM of antimicrobials and optimized administration of antibiotics are broadly used among respondents. The availability of antimicrobial susceptibility reports and a surveillance of antimicrobial use should be actively sought by intensivists where unavailable. Results of this survey may inform further research and educational activities.
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