Evidence map›Paper›PMID 34436634›Full record

ArticleArchives of microbiology2021

Marine macroalga-associated heterotrophic Bacillus velezensis: a novel antimicrobial agent with siderophore mode of action against drug-resistant nosocomial pathogens.

Kajal Chakraborty, Aneetta Francis, Rekha Devi Chakraborty, Sumayya Asharaf, Vinaya Kizhakkepatt Kizhakkekalam, Silpa Kunnappilly Paulose

Abstract read
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In one paragraph

Article in Archives of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  3. DecodingPlants (Basel, Switzerland) · 2026
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  4. Applied and environmental microbiology · 2025
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  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kajal ChakrabortyMarine Biotechnology Division, Central Marine Fisheries Research Institute, P.B. No. 1603, Ernakulam North, Cochin, India. kajal.chakraborty@icar.gov.in.ORCID http://orcid.org/0000-0002-7105-8942
Aneetta FrancisMarine Biotechnology Division, Central Marine Fisheries Research Institute, P.B. No. 1603, Ernakulam North, Cochin, India.
Rekha Devi ChakrabortyCrustacean Fisheries Division, Central Marine Fisheries Research Institute, P.B. No. 1603, Ernakulam North, Cochin, India.
Sumayya AsharafMarine Biotechnology Division, Central Marine Fisheries Research Institute, P.B. No. 1603, Ernakulam North, Cochin, India.
Vinaya Kizhakkepatt KizhakkekalamMarine Biotechnology Division, Central Marine Fisheries Research Institute, P.B. No. 1603, Ernakulam North, Cochin, India.
Silpa Kunnappilly PauloseMarine Biotechnology Division, Central Marine Fisheries Research Institute, P.B. No. 1603, Ernakulam North, Cochin, India.
Central Marine Fisheries Research Institute · INKerala Agricultural University · IN

Funding

College of Agriculture of Kerala Agricultural University, India under the B.Sc.-M.Sc. (Integrated) Biotechnology programme 2014-09-103Indian Council of Agricultural Research MBT/HLT/SUB23
6 · The paper itself

Abstract

Increased prevalence of microbial resistance and development of drug-resistant pathogens have triggered an urge among researchers to discover potential antimicrobial compounds, particularly from the marine habitat. The present study highlights the cultivable diversity and bioactivities of heterotrophic bacteria associated with marine macroalgae of southeast Indian coastal region. Culture-dependent isolation method resulted in 40 isolates, in which greater part of the isolates represented Gammaproteobacteria (62%) followed by that comprised of the phylum Firmicutes. One of the most active strains isolated from a macroalga, Laurencia papillosa, was characterized based on the integrated phenotypic and genotypic analysis as Bacillus velezensis MBTDLP1 MTCC 13048, with an inhibition zone of about 35 mm against methicillin-resistant Staphylococcus aureus (MRSA), was selected for bioprospecting studies. Type-I pks gene (MT394492) of 700 bp could be amplified from the heterotrophic B. velezensis. The bacterium exhibited siderophore production and possessed genes implicated in the biosynthesis of siderophore type of metabolites exhibiting 99% similarity with other GenBank sequences in BLAST search. B. velezensis exhibited promising anti-infective properties against methicillin-resistant Staphylococcus aureus (minimum inhibitory concentration 15 µg/mL), and the activities were positively correlated (r

Indexed as

Anti-Infective AgentsCross InfectionMethicillin-Resistant Staphylococcus aureusPharmaceutical PreparationsSeaweedAnti-Bacterial AgentsBacillusHumansMicrobial Sensitivity TestsProspective StudiesSiderophoresAnti-Bacterial AgentsAnti-Infective AgentsPharmaceutical PreparationsSiderophoresAntimicrobial agentBacillus velezensis MBTDLP1 MTCC 13048Iron-chelating activitiesMacrocyclic polyketideMarine macroalga-associated heterotrophic bacteria

Identifiers

PMID34436634
OpenAlexW3193687921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.