ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2021
A SNP-based GWAS and functional haplotype-based GWAS of flag leaf-related traits and their influence on the yield of bread wheat (Triticum aestivum L.).
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genome-wide meta-analysis of QTL for morphological related traits of flag leaf in bread wheat.PloS one · 2022Pooled it
- The functions of TaLAD1-A1, Rht8, and Rht-D1b in regulating leaf angle in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genetic dissection of cold stress tolerance and yield potential under cold stress in nested synthetic wheat (Triticum aestivum L.) introgression libraries using multi-locus genome-wide association and haplotype analysis.Functional & integrative genomics · 2026Article
- Genetic identification and characterization of novel loci for flag leaf morphology traits in Chinese endemic wheat.The plant genome · 2026Article
- The potential of wheat spatial omics.Nature genetics · 2026Review
- HaploVar: An R package for defining local haplotype variants for trait association and trait prediction analyses.Bioinformatics (Oxford, England) · 2025Article
- Dissecting the genetic architecture of flag leaf morphology in Sichuan Wheat Germplasm using genome-wide association study.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Review
- Genetic dissection of flag leaf morphology traits and fine mapping of a novel QTL (Qflw.sxau-6BL) in bread wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genomic regions associated with flag leaf and panicle architecture in rice (Oryza sativa L.).BMC genomics · 2024Article
- Characterization of flag leaf morphology identifies a major genomic region controlling flag leaf angle in the US winter wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genome-wide association study of trace elements in maize kernels.BMC plant biology · 2024Article
- Natural allelic variation confers diversity in the regulation of flag leaf traits in wheat.Scientific reports · 2024Article
- Fine-mapping and validation of the major quantitative trait locus QFlANG-4B for flag leaf angle in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genome-wide association study of kernel colour traits and mining of elite alleles from the major loci in maize.BMC plant biology · 2024Article
- A Wheat 660 K SNP array-based high-density genetic map facilitates QTL mapping of flag leaf-related traits in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Unraveling Genomic Regions Controlling Root Traits as a Function of Nitrogen Availability in the MAGIC Wheat Population WM-800.Plants (Basel, Switzerland) · 2022Article
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5 authors.
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Abstract
key messageThe genetic architecture of five flag leaf morphology traits was dissected by the functional haplotype-based GWAS and a standard SNP-based GWAS in a diverse population consisting of 197 varieties. Flag leaf morphology (FLM) is a critical factor affecting plant architecture and grain yield in wheat. The genetic architecture of FLM traits has been extensively studied with QTL mapping in bi-parental populations, while few studies exploited genome-wide association studies (GWAS) in diverse populations. In this study, a panel of 197 elite and historical varieties from China was evaluated for five FLM traits including the length (FLL), width (FLW), ratio (FLR), area (FLA) and angle (FLANG) as well as yield in nine environments. Based on the phenotypic correlation between yield and FLL (-0.43), FLA (- 0.32) and FLW (0.11), an empirical FLM index combining the three FLM traits proved to be a good predictor for yield. Two GWAS approaches were applied to dissect the genetic architecture of five FLM traits with a Wheat660K SNP array. The functional haplotype-based GWAS revealed 6, 5 and 7 QTL for FLANG, FLL and FLR, respectively, whereas two QTL for FLW and one for FLR were identified by the standard SNP-based GWAS. Due to co-localization, there were 18 independent QTL and 10 of them were close to known ones. One co-localized QTL on chromosome 5A was associated with FLL, FLANG and FLR. Moreover, both GWAS approaches identified a novel QTL for FLR on chromosome 6B which was not reported in previous studies. This study provides new insights into the relationship between FLM and yield and broadens our understanding of the genetic architecture of FLM traits in wheat.
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