Evidence map›Paper›PMID 34436476›Full record

ArticleMetabolites2021

Four Weeks of Probiotic Supplementation Alters the Metabolic Perturbations Induced by Marathon Running: Insight from Metabolomics.

Jamie N Pugh, Marie M Phelan, Eva Caamaño-Gutiérrez, S Andy Sparks, James P Morton, Graeme L Close, Daniel J Owens

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jamie N PughResearch Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool L3 3AF, UK.
Marie M PhelanNMR Metabolomics Shared Research Facility, Technology Directorate, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK.ORCID 0000-0002-0708-2964
Eva Caamaño-GutiérrezComputational Biology Facility, Technology Directorate, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK.
S Andy SparksSport Nutrition and Performance Research Group, Department of Sport and Physical Activity, Edge Hill University, Ormskirk L39 4QP, UK.
James P MortonResearch Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool L3 3AF, UK.
Graeme L CloseResearch Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool L3 3AF, UK.ORCID 0000-0002-7210-9553
Daniel J OwensResearch Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool L3 3AF, UK.ORCID 0000-0002-1908-8677
Liverpool John Moores University · GBUniversity of Liverpool · GBEdge Hill University · GB

Funding

CSRD VA 1
6 · The paper itself

Abstract

Few data are available that describe how probiotics influence systemic metabolism during endurance exercise. Metabolomic profiling of endurance athletes will elucidate mechanisms by which probiotics may confer benefits to the athlete. In this study, twenty-four runners (20 male, 4 female) were block randomised into two groups using a double-blind matched-pairs design according to their most recent Marathon performance. Runners were assigned to 28-days of supplementation with a multi-strain probiotic (PRO) or a placebo (PLB). Following 28-days of supplementation, runners performed a competitive track Marathon race. Venous blood samples and muscle biopsies (vastus lateralis) were collected on the morning of the race and immediately post-race. Samples were subsequently analysed by untargeted

Indexed as

exercisemarathonmetabolismmetabolomicsprobiotic

Identifiers

PMID34436476
PMCPMC8400326
OpenAlexW3189286530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.