Evidence map›Paper›PMID 34436468›Full record

ArticleMetabolites2021

An

Sara Ceccacci, Adriana De Lucia, Annalisa Tito, Assunta Tortora, Danila Falanga, Stefania Arciello, Giovanni Ausanio, Chiara Di Cicco, Maria Chiara Monti, Fabio Apone

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Cells · 2026
    Article
  2. Article
  3. Insights intoPharmaceuticals (Basel, Switzerland) · 2024
    Article
  4. Antioxidants (Basel, Switzerland) · 2022
    Article
  5. Promitotic Action ofInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sara CeccacciDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Adriana De LuciaArterra Bioscience SpA, 80142 Naples, Italy.
Annalisa TitoArterra Bioscience SpA, 80142 Naples, Italy.
Assunta TortoraArterra Bioscience SpA, 80142 Naples, Italy.
Danila FalangaArterra Bioscience SpA, 80142 Naples, Italy.
Stefania ArcielloArterra Bioscience SpA, 80142 Naples, Italy.
Giovanni AusanioCNR-SPIN Department of Physics, University of Naples "Federico II", 80125 Naples, Italy.
Chiara Di CiccoDepartment of Neuroscience and Reproductive and Odontostomatological Sciences, University of Naples "Federico II", 80131 Naples, Italy.
Maria Chiara MontiDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-1337-2909
Fabio AponeArterra Bioscience SpA, 80142 Naples, Italy.
University of Naples Federico II · ITUniversity of Salerno · IT

Funding

Ministero dello Sviluppo Economico Progetto di Ricerca Industriale e Sviluppo Sperimentale "Altergon Italia" 000463
6 · The paper itself

Abstract

Skin aging is a very well-known process setting a gradual worsening of skin mechanical features due to a decline in the production of the extra-cellular matrix machinery and to a concurrent change in the contraction process. To slow this progression, it is crucial to induce the expression of several proteins able to promote elastic fibers formation and tissue repair. Here, the

Indexed as

hydrophilic extract of Oenothera biennis cell culturesmatrix collagen contractionmetabolomicsmolecular networksskin aging

Identifiers

PMID34436468
PMCPMC8399800
OpenAlexW3187320863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.