Evidence map›Paper›PMID 34436459›Full record

ArticleMetabolites2021

Monitoring Early Glycolytic Flux Alterations Following Radiotherapy in Cancer and Immune Cells: Hyperpolarized Carbon-13 Magnetic Resonance Imaging Study.

Ying-Chieh Lai, Ching-Yi Hsieh, Kuan-Ying Lu, Cheng-Hsuan Sung, Hung-Yao Ho, Mei-Ling Cheng, Albert P Chen, Shu-Hang Ng, Fang-Hsin Chen, Gigin Lin

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Hyperpolarized [1-European radiology experimental · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ying-Chieh LaiDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0003-0148-9488
Ching-Yi HsiehClinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0002-9475-5169
Kuan-Ying LuDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0002-4677-9000
Cheng-Hsuan SungMedical Imaging Research Center, Institute for Radiological Research, Chang Gung University, Taoyuan 333, Taiwan.
Hung-Yao HoClinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0001-5990-6622
Mei-Ling ChengClinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0003-2006-133X
Albert P ChenGE Healthcare, Toronto, ON M5V 3Y3, Canada.
Shu-Hang NgDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0002-1842-6179
Fang-Hsin ChenDepartment of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-1671-4863
Gigin LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0001-7246-1058
Chang Gung University · TWChang Gung Memorial Hospital · TW

Funding

Chang Gung Medical Foundation BMRPF63,CLRPG3K0021,CMRPD1J0322,CMRPD1H0473Ministry of Science and Technology Taiwan MOST-109-2628-B-182-008, MOST107-2314-B-182A-059-MY2National Health Research Institutes Taiwan NHRI-109BCCO-MF-202009-02
6 · The paper itself

Abstract

Alterations in metabolism following radiotherapy affect therapeutic efficacy, although the mechanism underlying such alterations is unclear. A new imaging technique-named dynamic nuclear polarization (DNP) carbon-13 magnetic resonance imaging (MRI)-probes the glycolytic flux in a real-time, dynamic manner. The [1-

Indexed as

cancer metabolismdynamic nuclear polarizationglycolysisimmune systemmagnetic resonance imagingradiation

Identifiers

PMID34436459
PMCPMC8398834
OpenAlexW3189069156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.