Evidence map›Paper›PMID 34436438›Full record

ArticleMetabolites2021

High Throughput Procedure for Comparative Analysis of In Vivo Cardiac Glucose or Amino Acids Use in Cardiovascular Pathologies and Pharmacological Treatments.

Marta Tomczyk, Mariola Olkowicz, Ewa M Slominska, Ryszard T Smolenski

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marta TomczykDepartment of Biochemistry, Medical University of Gdansk, 80-210 Gdansk, Poland.ORCID 0000-0002-8934-9748
Mariola OlkowiczJagiellonian Centre for Experimental Therapeutics, 30-348 Krakow, Poland.
Ewa M SlominskaDepartment of Biochemistry, Medical University of Gdansk, 80-210 Gdansk, Poland.ORCID 0000-0002-3037-1844
Ryszard T SmolenskiDepartment of Biochemistry, Medical University of Gdansk, 80-210 Gdansk, Poland.ORCID 0000-0002-0190-9414
Gdańsk Medical University · PLJagiellonian University · PL

Funding

National Science Center in Poland 2016/23/B/NZ4/03877 and 2015/17/N/NZ4/028410
6 · The paper itself

Abstract

The heart is characterized by the prominent flexibility of its energy metabolism and is able to use diverse carbon substrates, including carbohydrates and amino acids. Cardiac substrate preference could have a major impact on the progress of cardiac pathologies. However, the majority of methods to investigate changes in substrates' use in cardiac metabolism in vivo are complex and not suitable for high throughput testing necessary to understand and reverse these pathologies. Thus, this study aimed to develop a simple method that would allow for the analysis of cardiac metabolic substrate use. The developed methods involved the subcutaneous injection of stable

Indexed as

catabolismheartmass spectrometry

Identifiers

PMID34436438
PMCPMC8398927
OpenAlexW3190518792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.