Evidence map›Paper›PMID 34436334›Full record

ArticleMembranes2021

Melatonin and Indole-3-Propionic Acid Reduce Oxidative Damage to Membrane Lipids Induced by High Iron Concentrations in Porcine Skin.

Aleksandra Rynkowska, Jan Stępniak, Małgorzata Karbownik-Lewińska

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Membranes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aleksandra RynkowskaDepartment of Oncological Endocrinology, Medical University of Lodz, 90-752 Łódź, Poland.
Jan StępniakDepartment of Oncological Endocrinology, Medical University of Lodz, 90-752 Łódź, Poland.ORCID 0000-0002-7547-6228
Małgorzata Karbownik-LewińskaDepartment of Oncological Endocrinology, Medical University of Lodz, 90-752 Łódź, Poland.
Medical University of Lodz · PL

Funding

Uniwersytet Medyczny w Lodzi 503/1-168-01/503-11-001
6 · The paper itself

Abstract

Iron excess in tissues results in increased oxidative damage. Among different tissues, the skin can particularly be severely damaged by oxidative stress, as it is exposed not only to endogenous but also directly to exogenous pro-oxidants. The skin is especially vulnerable to harmful oxidative stress. Melatonin and indole-3-propionic acid (IPA), two indole substances, are efficient antioxidants. This study aims to evaluate the potential protective effects of melatonin and IPA against oxidative damage to membrane lipids (lipid peroxidation (LPO)), induced in porcine skin homogenates by the Fenton reaction (Fe

Indexed as

Fenton reactionindole-3-propionic acidlipid peroxidationmelatoninmembrane lipidsoxidative stressskin

Identifiers

PMID34436334
PMCPMC8400501
OpenAlexW3183464947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.