Evidence map›Paper›PMID 34436266›Full record

ArticleMarine drugs2021

Screening of Neutrophil Activating Factors from a Metagenome Library of Sponge-Associated Bacteria.

Yoshiko Okamura, Hirokazu Takahashi, Atsuyuki Shiida, Yuto Hirata, Haruko Takeyama, Katsuhiko Suzuki

Abstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yoshiko OkamuraGraduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima 739-8530, Japan.ORCID 0000-0001-8333-7722
Hirokazu TakahashiGraduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima 739-8530, Japan.
Atsuyuki ShiidaGraduate School of Advanced Sciences of Matter, Hiroshima University, Higashihiroshima 739-8530, Japan.
Yuto HirataGraduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima 739-8530, Japan.
Haruko TakeyamaDepartment of Life Science and Medical Bio-Science, Waseda University, Tokyo 162-8480, Japan.
Katsuhiko SuzukiFaculty of Sport Sciences, Waseda University, Saitama 359-1192, Japan.ORCID 0000-0002-6572-5809

Funding

Japan Society for the Promotion of Science 24560964
6 · The paper itself

Abstract

Marine sponge-associated bacteria are known as bio-active compound produce. We have constructed metagenome libraries of the bacteria and developed a metagenomic screening approach. Activity-based screening successfully identified novel genes and novel enzymes; however, the efficiency was only in 1 out of 10

Indexed as

AnimalsAquatic OrganismsBacteriaGene LibraryMetagenomicsNeutrophilsPoriferaactivity-based screeningbioactive compoundmetagenome analysisneutrophil activating peptide

Identifiers

PMID34436266
PMCPMC8402132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.