ArticleJournal of cardiovascular development and disease2021
Fat-to-Muscle Ratios and the Non-Achievement of LDL Cholesterol Targets: Analysis of the Korean Genome and Epidemiology Study.
Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- [Total and regional fat-to-muscle mass ratio and risk of incident benign ovarian neoplasm].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Body Muscle-to-Fat Ratio (BMFR) as a Promising Anthropometric Index for Use in the Evaluation of Insulin Resistance and Metabolic Disease Risk: a Narrative Review.Current obesity reports · 2025Review
- Relationships of Fat Mass Index and Fat-Free Mass Index with Low-Density Lipoprotein Cholesterol Levels in the Tohoku Medical Megabank Community-Based Cohort Study.Journal of atherosclerosis and thrombosis · 2024Article
- Article
- Fat-to-muscle ratio as a predictor for dyslipidaemia in transitional-age youth.Lipids in health and disease · 2022Article
- Nutritional Influences on Locomotive Syndrome.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Maintaining optimal low-density lipoprotein (LDL) cholesterol levels is necessary to prevent cardiovascular disease (CVD). Excessive fat mass and decreased muscle mass are both associated with increased risks of developing dyslipidemia. Thus, we investigated the longitudinal relationship between the fat-to-muscle ratio (FMR) and the non-achievement of LDL cholesterol targets. We analyzed a total of 4386 participants aged 40-69 years from the Korean Genome and Epidemiology Study. FMR was defined as the ratio of total fat mass to total muscle mass, measured by bioelectrical impedance. The non-achievement of an LDL cholesterol target was defined as an LDL cholesterol level higher than the established target level according to individual CVD risk. The adjusted hazard ratios and 95% confidence interval for the incidence of non-achievement of LDL cholesterol targets for the sex-specific middle and highest tertiles vs. the referent lowest tertile of FMR were 1.56 (1.29-1.90) and 1.86 (1.47-2.31) in men and 1.40 (1.18-1.66) and 1.31 (1.06-1.62) in women after adjusting confounders. Our findings suggest that FMR, a novel indicator of the combined effects of fat and muscle mass, is useful for predicting non-achievement of LDL cholesterol targets.
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