Evidence map›Paper›PMID 34436227›Full record

ArticleJournal of cardiovascular development and disease2021

The Effect of Vitamin D on Coronary Atherosclerosis: A Propensity Score Matched Case-Control Coronary CTA Study.

Gudrun Feuchtner, Simon Suppersberger, Christian Langer, Christoph Beyer, Stefan Rauch, Theresa Thurner, Guy Friedrich, Wolfgang Dichtl, Gerlig Widmann, Fabian Plank and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Gudrun FeuchtnerDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-6755-4399
Simon SuppersbergerDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christian LangerDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christoph BeyerDepartment of Internal Medicine III, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Stefan RauchDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Theresa ThurnerGesundheitszentrum Lanserhof, 6072 Lans, Austria.
Guy FriedrichDepartment of Internal Medicine III, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Wolfgang DichtlDepartment of Internal Medicine III, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-0421-2110
Gerlig WidmannDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Fabian PlankDepartment of Internal Medicine III, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-1861-9480
Fabian BarbieriDepartment of Internal Medicine III, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-4456-1822
Innsbruck Medical University · ATGesundheitszentrum Oberndorf · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D supplementation may be associated with lower cardiovascular (CV) events, but the data are controversial. It remains speculative whether vitamin D supplementation has a direct effect on coronary atherosclerosis. We therefore set out to assess the influence of vitamin D supplementation on the coronary atherosclerosis profile quantified by coronary computed tomography angiography (CTA) in a retrospective case-control cohort study.

methods176 patients (age: 62.4 ± 10.4) referred to coronary CTA for clinical indications were included. A total of 88 patients receiving vitamin D supplementation (mean duration 65.3 ± 81 months) were 1:1 propensity score matched with 88 controls for age, gender, smoking, arterial hypertension, positive family history, dyslipidemia, and diabetes. Coronary stenosis severity (CAD-RADS

resultsThe prevalence of atherosclerosis by CTA was similar in both groups (75.6% versus 74.3%,

conclusionsIn this retrospective case-control cohort study, vitamin D supplementation was associated with less high-risk plaque, less non-calcified plaque burden, and a higher calcified plaque independent of CV risk factors.

Indexed as

atherosclerosiscardiovascular disease preventioncoronary computed tomography angiographyimagingpropensity score matchmakingvitamin D

Identifiers

PMID34436227
PMCPMC8397201
OpenAlexW3185984634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.