Evidence map›Paper›PMID 34436225›Full record

ArticleJournal of cardiovascular development and disease2021

Efficacy of Drug-Eluting Stents in Diabetic Patients Admitted with ST-Elevation Myocardial Infarctions Treated with Primary Percutaneous Coronary Intervention.

Johannes Schmucker, Andreas Fach, Rico Osteresch, Luis Alberto Mata Marin, Stephan Ruehle, Tina Retzlaff, Daniela Garstka, Ingo Eitel, Rainer Hambrecht, Harm Wienbergen

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Impact of Diabetes on Long-Term Outcomes of Percutaneous Coronary Intervention for Coronary Bifurcation Lesions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Johannes SchmuckerBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
Andreas FachBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
Rico OstereschBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
Luis Alberto Mata MarinBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
Stephan RuehleBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.ORCID 0000-0001-9901-9462
Tina RetzlaffBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
Daniela GarstkaBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
Ingo EitelMedical Clinic II, University Heart Center, 23562 Lübeck, Germany.
Rainer HambrechtBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
Harm WienbergenBremen Institute for Heart and Circulation Research, 28277 Bremen, Germany.
University of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic patients show higher adverse ischemic event rates and mortality when undergoing percutaneous coronary intervention (PCI) in acute myocardial infarctions. Therefore, diabetic patients might benefit even more from modern-generation drug-eluting stents (DES). The aim of the present study was to compare adverse ischemic events and mortality rates between bare-metal stents (BMS) and DES in diabetic patients admitted with ST-elevation-myocardial infarction (STEMI) with non-diabetic patients as the control group.

methodsAll STEMI patients undergoing emergency PCI and stent implantation documented between 2006 and 2019 in the Bremen STEMI registry entered the analysis. Efficacy was defined as a combination of in-stent thrombosis, myocardial re-infarction or additional target lesion revascularization at one year.

resultsOf 8356 patients which entered analysis, 1554 (19%) were diabetics, while 6802 (81%) were not. 879 (57%) of the diabetics received a DES. In a multivariate model, DES implantation in diabetics compared to BMS was associated with lower rates of in-stent thrombosis (OR 0.16, 95% CI 0.05-0.6), myocardial re-infarctions (OR 0.35, 95%CI, 0.2-0.7,

conclusionsIn STEMI patients with diabetes, the use of DES significantly reduced ischemic event rates and, unlike with BMS, adverse ischemic event rates became similar to non-diabetic patients.

Indexed as

coronary artery diseasediabetes mellitusdrug-eluting stentsSTEMI

Identifiers

PMID34436225
PMCPMC8397182
OpenAlexW3183168753

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.