Evidence map›Paper›PMID 34436082›Full record

ReviewBiosensors2021

Recent Development of Nanomaterials-Based Cytosensors for the Detection of Circulating Tumor Cells.

Zhi-Fang Sun, Yong Chang, Ning Xia

Abstract readReview
In one paragraph

Review in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhi-Fang SunCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Yong ChangCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Ning XiaCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.ORCID 0000-0003-0366-7524

Funding

National Natural Science Foundation of China 21905002Program for Innovative Research Team of Science and Technology in the University of Henan Province 21IRTSTHN005
6 · The paper itself

Abstract

The accurate analysis of circulating tumor cells (CTCs) holds great promise in early diagnosis and prognosis of cancers. However, the extremely low abundance of CTCs in peripheral blood samples limits the practical utility of the traditional methods for CTCs detection. Thus, novel and powerful strategies have been proposed for sensitive detection of CTCs. In particular, nanomaterials with exceptional physical and chemical properties have been used to fabricate cytosensors for amplifying the signal and enhancing the sensitivity. In this review, we summarize the recent development of nanomaterials-based optical and electrochemical analytical techniques for CTCs detection, including fluorescence, colorimetry, surface-enhanced Raman scattering, chemiluminescence, electrochemistry, electrochemiluminescence, photoelectrochemistry and so on.

Indexed as

Biosensing TechniquesNeoplastic Cells, CirculatingAptamers, NucleotideCell CountElectrochemical TechniquesFluorescenceHumansNanostructuresSpectrum Analysis, RamanAptamers, Nucleotidecancer biomarkerscirculating tumor cellselectrochemical biosensorsnanomaterialsoptical biosensors

Identifiers

PMID34436082
PMCPMC8391755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.