ArticleBiosensors2021
Polymer Optical Waveguide Grating-Based Biosensor to Detect Effective Drug Concentrations of Ginkgolide A for Inhibition of PMVEC Apoptosis.
Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Application of biosensors in research of traditional Chinese medicine: a systematic review.Chinese medicine · 2026Review
- A Review on Photonic Sensing Technologies: Status and Outlook.Biosensors · 2023Review
- Advances in Waveguide Bragg Grating Structures, Platforms, and Applications: An Up-to-Date Appraisal.Biosensors · 2022Review
- Electro-Optical Biosensor Based on Embedded Double-Monolayer of Graphene Capacitor in Polymer Technology.Polymers · 2021Article
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Authors and funding
8 authors.
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Abstract
In this work, we successfully developed a fluorinated cross-linked polymer Bragg waveguide grating-based optical biosensor to detect effective drug concentrations of ginkgolide A for the inhibition of pulmonary microvascular endothelial cell (PMVEC) apoptosis. Fluorinated photosensitive polymer SU-8 (FSU-8) as the sensing core layer and polymethyl methacrylate (PMMA) as the sensing window cladding were synthesized. The effective drug concentration range (5-10 µg/mL) of ginkgolide A for inhibition of PMVEC apoptosis was analyzed and obtained by pharmacological studies. The structure of the device was optimized to be designed and fabricated by direct UV writing technology. The properties of the biosensor were simulated with various refractive indices of different drug concentrations. The actual sensitivity of the biosensor was measured as 1606.2 nm/RIU. The resolution and detection limit were characterized as 0.05 nm and 3 × 10
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Registered trials
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