Evidence map›Paper›PMID 34436050›Full record

ArticleBiosensors2021

Bioelectromagnetic Platform for Cell, Tissue, and In Vivo Stimulation.

Ryan C Ashbaugh, Lalita Udpa, Ron R Israeli, Assaf A Gilad, Galit Pelled

Abstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Genetics-Based Targeting Strategies for Precise Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan C AshbaughDepartment of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-2671-1954
Lalita UdpaDepartment of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-2007-0244
Ron R IsraeliNeuroengineering Division, Michigan State University, East Lansing, MI 48824, USA.
Assaf A GiladDepartment of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-7272-7570
Galit PelledNeuroengineering Division, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-2692-2882

Funding

The Role of the Transcallosal Pathway in Neuroplasticity Following Nerve InjuryR01NS072171 · NINDS · MICHIGAN STATE UNIVERSITY · PI PELLED, GALIT · 2010 to 2019
$3.5M
Bioengineering a novel electromagnetic perspective gene as a tool for wireless control of excitable cellsR01NS098231 · NINDS · MICHIGAN STATE UNIVERSITY · PI GILAD, ASSAF A, PELLED, GALIT · 2017 to 2021
$2.6M
Adaptive control of epileptic seizures using a genetically encoded sensorR01NS079288 · NINDS · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI GILAD, ASSAF A, PELLED, GALIT · 2012 to 2015
$1.4M
Molecular Imaging for Detection of Synthetic Biology Circuits, Oscillators and Toggle Switches in Regenerative MedicineR01NS104306 · NINDS · MICHIGAN STATE UNIVERSITY · PI GILAD, ASSAF A · 2018 to 2021
$1.3M
NINDS NIH HHS R01NS072171NINDS NIH HHS R01 NS079288NINDS NIH HHS R01 NS098231NINDS NIH HHS R01NS098231NINDS NIH HHS R01NS104306
6 · The paper itself

Abstract

Magnetogenetics is a new field that utilizes electromagnetic fields to remotely control cellular activity. In addition to the development of the biological genetic tools, this approach requires designing hardware with a specific set of demands for the electromagnets used to provide the desired stimulation for electrophysiology and imaging experiments. Here, we present a universal stimulus delivery system comprising four magnet designs compatible with electrophysiology, fluorescence and luminescence imaging, microscopy, and freely behaving animal experiments. The overall system includes a low-cost stimulation controller that enables rapid switching between active and sham stimulation trials as well as precise control of stimulation delivery thereby enabling repeatable and reproducible measurements.

Indexed as

ElectrophysiologyIn Vitro TechniquesAnimalsComputer SimulationElectromagnetic Fieldshead-fixed experimentshigh-throughput magnetogeneticsin vivo stimulationminimally-invasive brain stimulationneuromodulation

Identifiers

PMID34436050
PMCPMC8392012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.