Evidence map›Paper›PMID 34436023›Full record

ReviewCurrent oncology (Toronto, Ont.)2021

Extreme Hypofractionation with SBRT in Localized Prostate Cancer.

Maria Antonia Gómez-Aparicio, Jeannette Valero, Begoña Caballero, Rafael García, Ovidio Hernando-Requejo, Ángel Montero, Alfonso Gómez-Iturriaga, Thomas Zilli, Piet Ost, Fernando López-Campos and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. PSA reduction as predictor of biochemical relapse in low and favourable intermediate prostate cancer treated with radical radiotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. The Proteogenomics of Prostate Cancer Radioresistance.Cancer research communications · 2024
    Article
  9. Weekly ultra-hypofractionated radiotherapy in localised prostate cancer.Clinical and translational radiation oncology · 2024
    Article
  10. Article
  11. Current Evidence on Local Therapies in Advanced Adrenocortical Carcinoma.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 3 countries.

Maria Antonia Gómez-AparicioDepartment of Radiation Oncology, Hospital Universitario de Toledo, 45007 Toledo, Spain.
Jeannette ValeroDepartment of Radiation Oncology, Hospital Universitario HM Sanchinarro, 28050 Madrid, Spain.
Begoña CaballeroDepartment of Radiation Oncology, Hospital Universitario de Fuenlabrada, 28942 Fuenlabrada, Spain.
Rafael GarcíaDepartment of Radiation Oncology, Hospital Ruber Internacional, 28034 Madrid, Spain.
Ovidio Hernando-RequejoDepartment of Radiation Oncology, Hospital Universitario HM Sanchinarro, 28050 Madrid, Spain.
Ángel MonteroDepartment of Radiation Oncology, Hospital Universitario HM Sanchinarro, 28050 Madrid, Spain.ORCID 0000-0001-5566-0493
Alfonso Gómez-IturriagaDepartment of Radiation Oncology, Cruces University Hospital, 48903 Barakaldo, Spain.
Thomas ZilliDepartment of Radiation Oncology, Geneva University Hospital, 1205 Geneva, Switzerland.ORCID 0000-0002-4784-9883
Piet OstDepartment of Radiation Oncology, Ghent University Hospital, 9000 Ghent, Belgium.
Fernando López-CamposDepartment of Radiation Oncology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-4077-0507
Felipe CouñagoDepartment of Radiation Oncology, Hospital Universitario Quirónsalud, 28223 Madrid, Spain.ORCID 0000-0001-7233-0234
Hospital Universitario HM Sanchinarro · ESComplejo Hospitalario Universitario de Toledo · ESGhent University Hospital · BEHospital de Cruces · ESHospital La Luz · ESHospital Ruber Internacional · ESHospital Universitario de Fuenlabrada · ESHospital Universitario Ramón y Cajal · ESUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the most commonly diagnosed cancer among men around the world. Radiotherapy is a standard of care treatment option for men with localized prostate cancer. Over the years, radiation delivery modalities have contributed to increased precision of treatment, employing radiobiological insights to shorten the overall treatment time, improving the control of the disease without increasing toxicities. Stereotactic body radiation therapy (SBRT) represents an extreme form of hypofractionated radiotherapy in which treatment is usually delivered in 1-5 fractions. This review assesses the main efficacy and toxicity data of SBRT in non-metastatic prostate cancer and discusses the potential to implement this scheme in routine clinical practice.

Indexed as

Prostatic NeoplasmsRadiosurgeryRadiotherapy, Intensity-ModulatedHumansMaleRadiation Dose Hypofractionationextreme hypofractionationhypofractionationprostate cancerstereotactic body radiation therapy (SBRT)

Identifiers

PMID34436023
PMCPMC8395496
OpenAlexW3188177793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.