ArticlePsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2021
Effect of alcohol, tobacco, and cannabis co-use on gray matter volume in heavy drinkers.
Article in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Assessment of contextualized reinforcement pathology in a community sample of young adult substance users.Alcohol, clinical & experimental research · 2025Article
- Effects of alcohol and cannabis co-use on salience network resting state functional connectivity in individuals who drink alcohol heavily.Drug and alcohol dependence · 2025Article
- The effects of alcohol use severity and polygenic risk on gray matter volumes in young adults.medRxiv : the preprint server for health sciences · 2025Article
- The effects of alcohol use severity and polygenic risk on gray matter volumes in young adults.Frontiers in psychiatry · 2025Article
- Association Between Cannabis Use and Brain Structures: A Mendelian Randomization Study.Cureus · 2024Article
- Regional cortical brain volumes at treatment entry relates to post treatment WHO risk drinking levels in those with alcohol use disorder.Drug and alcohol dependence · 2024Article
- The role of sex in daily levels of high-risk alcohol and cannabis co-use.Drug and alcohol dependence reports · 2023Article
- Associations of daily alcohol, cannabis, combustible tobacco, and e-cigarette use with same-day co-use and poly-use of the other substances.Drug and alcohol dependence · 2023Article
- Socioeconomic Inequalities in Alcohol and Tobacco Consumption: A National Ecological Study in Mexican Adolescents.TheScientificWorldJournal · 2023Article
- Prevalence and factors associated with substance use among HIV positive youth attending HIV care and treatment centers in Dodoma, Tanzania.AIDS research and therapy · 2022Article
- Article
- Combined use of alcohol and cannabis: Introduction to the special issue.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectiveAlcohol, tobacco, and cannabis are the three most frequently used drugs in the United States and co-use is common. Alcohol, tobacco, and cannabis use has been separately associated with altered brain structure, and alcohol and tobacco co-use results in decreases in gray matter volume. Less is known about the effect of alcohol and cannabis co-use, and alcohol, tobacco, and cannabis tri-use. Therefore, this study examined the effect of co- and tri-use on gray matter volume, a measure of brain cell density, in heavy drinkers.
methodHeavy drinkers (
resultsAlcohol and tobacco co-users had significantly decreased left orbitofrontal gray matter volume relative to alcohol only users (Cohen's
conclusionThe additive effect of tobacco co-use on gray matter volumes in heavy drinkers was limited and localized. The effect of tri-use of alcohol, tobacco, and cannabis may have interacted, such that overlapping cannabis and tobacco use masked volume differences present in separate co-using groups. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.