Evidence map›Paper›PMID 34435508›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Human adipose and skeletal muscle tissue DNA, RNA, and protein content.

Andrew M Stroh, Colleen E Lynch, Bridget E Lester, Kiril Minchev, Toby L Chambers, Cristhian F Montenegro, Clarisa Chavez Martinez, William A Fountain, Todd A Trappe, Scott W Trappe

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Human Adipose Allograft Restores Volume Through Host-mediated Tissue Replacement.Plastic and reconstructive surgery. Global open · 2026
    Article
  2. Article
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  4. Article
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  9. Muscle Proteome Dynamics.Advances in experimental medicine and biology · 2025
    Review
  10. Article
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  12. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Andrew M StrohHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Colleen E LynchHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Bridget E LesterHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Kiril MinchevHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Toby L ChambersHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Cristhian F MontenegroHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Clarisa Chavez MartinezHuman Performance Laboratory, Ball State University, Muncie, Indiana.
William A FountainHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Todd A TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Scott W TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana.ORCID 0000-0002-6438-431X
Ball State University · US

Funding

The Exercise and Physical Activity Collaborative Team (ExPACT): a Proposed MoTrPAC Clinical CenterU01AR071133 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BUFORD, THOMAS W, GOODPASTER, BRET H · 2017 to 2024
$16.7M
NIAMS NIH HHS U01 AR071133NIH HHS U01AR071133
6 · The paper itself

Abstract

The purpose of this project was to provide a profile of DNA, RNA, and protein content in adipose tissue, which is relatively understudied in humans, to gain more insight into the amount of tissue that may be required for various analyses. Skeletal muscle tissue was also investigated to provide a direct comparison into potential differences between these two highly metabolically active tissues. Basal adipose and skeletal muscle tissue samples were obtained from 10 (7 M, 3 W) recreationally active participants [25 ± 1 yr; 84 ± 3 kg, maximal oxygen consumption (V̇o

Indexed as

Muscle, SkeletalRNAAdipose TissueDNAExerciseHumansDNARNAadiposeDNAproteinRNAskeletal muscle

Identifiers

PMID34435508
PMCPMC8560392
OpenAlexW3195716951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.