ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2022
Long-term opioid use in seniors following hip and knee arthroplasty in Ontario: a historical cohort study.
Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Predictors and Clinical Outcomes of Long-Term Opioid Therapy in Older Adults: A Systematic Review.Pharmacotherapy · 2026Pooled it
- Risk factors for long-term analgesic prescription after hip or knee arthroplasty for osteoarthritis: results of a multivariable regression analysis based on health insurance claims data from 137,875 patients with postoperative inpatient rehabilitation.BMC musculoskeletal disorders · 2026Article
- Association of preoperative corticosteroids with persistent opioid requirements following total knee arthroplasty: an exploratory population-based cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Prediction Model for Factors Associated With Long-Term Opioid Use Following Total Knee Arthroplasty: A Retrospective Population-Based Study.European journal of pain (London, England) · 2026Article
- Development and validation of a clinically available risk model for medium-to-high opioid consumption after total knee arthroplasty.American journal of translational research · 2026Article
- Pain profiles and opioid consumption following joint replacement surgery: a prospective observational cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Observational
- Postoperative joint pain is associated with long-term all-cause mortality after total joint arthroplasty.PloS one · 2025Article
- Postoperative opioid consumption and prescription in major abdominal surgery.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- In reply: Use of a provincial prescription monitoring database to characterize perioperative opioid prescribing for hip and knee arthroplasty.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Article
- Use of a provincial prescription monitoring database to characterize perioperative opioid prescribing for hip and knee arthroplasty.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Article
- Chronic opioid use after joint replacement surgery in seniors is associated with increased healthcare utilization and costs: a historical cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Article
- Postdischarge opioid use after lumbar spine surgery among older adults in Ontario: a population-based cohort study.Canadian journal of surgery. Journal canadien de chirurgieArticle
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9 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeCanadian seniors who undergo hip and knee arthroplasty often experience significant postoperative pain, which could result in persistent opioid use. We aimed to document the impact of preoperative opioid use and other characteristics on postoperative opioid prescriptions in elderly patients following hip and knee replacement before widespread dissemination of opioid reduction strategies.
methodsWe conducted a historical cohort study to evaluate postoperative opioid use in patients over 65 yr undergoing primary total hip and knee replacement over a ten-year period from 1 April 2006 to 31 March 2016, using linked de-identified Ontario administrative data. We determined the use of preoperative opioids and the duration of postoperative opioid prescriptions (short-term [1-90 days], prolonged [91-180 days], chronic [181-365 days], or undocumented).
resultsThe study included 49,638 hip and 85,558 knee replacement patients. Eighteen percent of hip and 21% of knee replacement patients received an opioid prescription within 90 days before surgery. Postoperatively, 51% of patients filled opioid prescriptions for 1-90 days, while 24% of hip and 29% of knee replacement patients filled prescriptions between 6 and 12 months, with no impact of preoperative opioid use. Residence in long-term care was a significant predictor of chronic opioid use (hip: odds ratio [OR], 2.64; 95% confidence interval [CI], 1.93 to 3.59; knee: OR, 2.46; 95% CI, 1.75 to 3.45); other risk factors included female sex and increased comorbidities.
conclusionDespite a main goal of joint arthroplasty being relief of pain, seniors commonly remained on postoperative opioids, even if not receiving opioids before surgery. Opioid reduction strategies need to be implemented at the surgical, primary physician, long-term care, and patient levels. These findings form a basis for future investigations following implementation of opioid reduction approaches.
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