Evidence map›Paper›PMID 34435246›Full record

ReviewEuropean radiology experimental2021

MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond.

Behroze Vachha, Susie Y Huang

Open access · goldAbstract readReview
In one paragraph

Review in European radiology experimental, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.

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  19. Utilizing TMaterials (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Behroze VachhaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA.
Susie Y HuangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149 13th Street, Room 2301, Charlestown, MA, 02129, USA. susie.huang@mgh.harvard.edu.ORCID 0000-0003-2950-7254
Massachusetts General Hospital · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
CONNECTOME 2.0: DEVELOPING THE NEXT GENERATION HUMAN MRI SCANNER FOR BRIDGING STUDIES OF THE MICRO-, MESO- AND MACRO-CONNECTOMEU01EB026996 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BASSER, PETER J., HUANG, SUSIE YI · 2018 to 2022
$14.2M
Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2020 to 2026
$10.9M
Toward a Validated in Vivo Imaging Marker of Axonal Damage Predictive of Progressive Disability in Multiple SclerosisR01NS118187 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HUANG, SUSIE YI · 2021 to 2025
$2.8M
Characterizing axonal damage in multiple sclerosis using TractCaliber MRIK23NS096056 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HUANG, SUSIE YI · 2016 to 2020
$877k
Exploring the Relationship Between Tau Deposition and Neurovascular Health in Alzheimer's DiseaseR21AG067562 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HUANG, SUSIE YI, YEN, YI-FEN · 2020 to 2020
$462k
NCI NIH HHS P30 CA008748NIA NIH HHS R21 AG067562NIBIB NIH HHS P41 EB030006NIBIB NIH HHS U01 EB026996NINDS NIH HHS K23 NS096056NINDS NIH HHS R01 NS118187
6 · The paper itself

Abstract

Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology has provided enormous gains in sensitivity, resolution, and contrast for neuroimaging. This article provides an overview of the technical advantages and challenges of performing clinical neuroimaging studies at ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology. Emerging clinical applications of 7-T MRI and state-of-the-art gradient systems equipped with up to 300 mT/m gradient strength are reviewed, and the impact and benefits of such advances to anatomical, structural and functional MRI are discussed in a variety of neurological conditions. Finally, an outlook and future directions for ultrahigh field MRI combined with ultrahigh and ultrafast gradient technology in neuroimaging are examined.

Indexed as

Magnetic Resonance ImagingNeuroimagingEpilepsyMagnetic fieldsMagnetic resonance imagingMultiple sclerosisNeuroimaging

Identifiers

PMID34435246
PMCPMC8387544
OpenAlexW3195563439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.