ArticleMetabolomics : Official journal of the Metabolomic Society2021
Systematic selection of competing metabolomics methods in a metabolite-sensory relationship study.
Article in Metabolomics : Official journal of the Metabolomic Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Flavor Profiling Using Comprehensive Mass Spectrometry Analysis of Metabolites in Tomato Soups.Metabolites · 2022Article
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10 authors.
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Abstract
introductionThe relationship between the chemical composition of food products and their sensory profile is a complex association confronting many challenges. However, new untargeted methodologies are helping correlate metabolites with sensory characteristics in a simpler manner. Nevertheless, in the pilot phase of a project, where only a small set of products are used to explore the relationships, choices have to be made about the most appropriate untargeted metabolomics methodology.
objectiveTo provide a framework for selecting a metabolite-sensory methodology based on: the quality of measurements, the relevance of the detected metabolites in terms of distinguishing between products or in terms of whether they can be related to the sensory attributes of the products.
methodsIn this paper we introduce a systematic approach to explore all these different aspects driving the choice for the most appropriate metabolomics method.
resultsAs an example we have used a tomato soup project where the choice between two sampling methods (SPME and SBSE) had to be made. The results are not always consistently pointing to the same method as being the best. SPME was able to detect metabolites with a better precision, SBSE seemed to be able to provide a better distinction between the soups.
conclusionThe three levels of comparison provide information on how the methods could perform in a follow up study and will help the researcher to make a final selection for the most appropriate method based on their strengths and weaknesses.
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