Evidence map›Paper›PMID 34435228›Full record

ReviewAbdominal radiology (New York)2022

Radiomics: a primer on high-throughput image phenotyping.

Kyle J Lafata, Yuqi Wang, Brandon Konkel, Fang-Fang Yin, Mustafa R Bashir

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Development and validation of anAnnals of nuclear medicine · 2025
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  12. Association of Pancreas Volume With Adverse Clinical Outcomes.Journal of the American Heart Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyle J LafataDepartment of Radiology, Duke University School of Medicine, Durham, NC, USA. kyle.lafata@duke.edu.ORCID http://orcid.org/0000-0002-4513-6249
Yuqi WangDepartment of Electrical & Computer Engineering, Duke University Pratt School of Engineering, Durham, NC, USA.
Brandon KonkelDepartment of Radiology, Duke University School of Medicine, Durham, NC, USA.
Fang-Fang YinDepartment of Radiation Oncology, Duke University School of Medicine, Durham, NC, USA.
Mustafa R BashirDepartment of Radiology, Duke University School of Medicine, Durham, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiomics is a high-throughput approach to image phenotyping. It uses computer algorithms to extract and analyze a large number of quantitative features from radiological images. These radiomic features collectively describe unique patterns that can serve as digital fingerprints of disease. They may also capture imaging characteristics that are difficult or impossible to characterize by the human eye. The rapid development of this field is motivated by systems biology, facilitated by data analytics, and powered by artificial intelligence. Here, as part of Abdominal Radiology's special issue on Quantitative Imaging, we provide an introduction to the field of radiomics. The technique is formally introduced as an advanced application of data analytics, with illustrating examples in abdominal radiology. Artificial intelligence is then presented as the main driving force of radiomics, and common techniques are defined and briefly compared. The complete step-by-step process of radiomic phenotyping is then broken down into five key phases. Potential pitfalls of each phase are highlighted, and recommendations are provided to reduce sources of variation, non-reproducibility, and error associated with radiomics.

Indexed as

Artificial IntelligenceRadiologyAlgorithmsHumansImage Processing, Computer-AssistedRadiographyArtificial intelligenceBiomarkersImage-based phenotypingMachine learningRadiomics

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.