Evidence map›Paper›PMID 34435060›Full record

ArticleIranian journal of biotechnology2021

Evaluation of

Shirin Lotfipanah, Parichehreh Yaghmaei, Majid Zeinali, Seyed Ali Haeri Rohani, Sosan Kabodanian Ardestani

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shirin LotfipanahDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Parichehreh YaghmaeiDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Majid ZeinaliBiotechnology Research Center, Research Institute of Petroleum Industry (RIPI), Tehran, Iran.
Seyed Ali Haeri RohaniDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Sosan Kabodanian ArdestaniInstitute of Biochemistry and Biophysics, Research institute in Tehran University, Tehran, Iran.
Islamic Azad University, Science and Research Branch · IRBiotechnology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNanomaterials, e.g.carbon nanotubes (CNTs), have broad usage in medicine for diagnosis, treatment, and drug delivery. Prior to the widespread use of CNTs, any potential toxicity issues must be considered. Apoptosis is an important issue in toxicological studies, and tumor necrosis factor (TNF) family members execute crucial roles in apoptosis and inflammation. We examined the survival of Jurkat cells under the influence of single-walled CNTs (SWCNTs) and multi-walled CNTs (MWCNTs) as well as their impacts on the mRNA levels of TNF family transcripts in Jurkat cells and rats.

objectiveTo evaluate the toxicity or safety of a specific concentration and form of CNT on the expression of one of the gene families of the apoptotic pathway. MATERIALS AND

methodsJurkat cells were exposed to SWCNTs and MWCNTs in carboxylated form (SWCNTS-COOH and MWCNTs-COOH). MTT assay assessed the cell survival, and using qRT-PCR, the expression levels of

resultsAfter 72 h of carboxylated CNTs at 100 µg. mL

conclusionsAdministration of SWCNTs-COOH and MWCNTs-COOH could result in the up-regulation of

Indexed as

CNTSGene ExpressionJurkat CellTNF Family

Identifiers

PMID34435060
PMCPMC8358176
OpenAlexW3184860851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.