ReviewFrontiers in cardiovascular medicine2021
Atrial Cardiomyopathy: An Emerging Cause of the Embolic Stroke of Undetermined Source.
Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Phenotypic determinants of atrial fibrillation in ischaemic stroke: a retrospective study.Open heart · 2026Article
- Atrial cardiopathy and thrombus composition in acute ischemic stroke: histological examination reveals insights into etiology and outcomes.Journal of thrombosis and thrombolysis · 2026Article
- Atrial Cardiomyopathy: A "Distinct Clinical Entity" for a Deeper Understanding of Atrial Fibrillation and Cardioembolic Stroke.Journal of clinical medicine · 2025Review
- Brazilian Atrial Fibrillation Guidelines - 2025.Arquivos brasileiros de cardiologia · 2025Article
- Estimated Glucose Disposal Rate and Risk of Stroke and Dementia in Nondiabetics: A UK Biobank Prospective Cohort Study.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
- 2025 THRS Expert Consensus of Imaging Assessment in Atrial Fibrillation.Acta Cardiologica Sinica · 2025Article
- Immune Regulation in Atrial Cardiomyopathy.Reviews in cardiovascular medicine · 2025Review
- Bradyarrhythmias in patients with embolic stroke of undetermined source: a tight relationship with atrial cardiomyopathy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Brain natriuretic peptide and echocardiographic parameters as biomarkers for predicting new atrial fibrillation detection after acute ischemic stroke.Therapeutic advances in neurological disorders · 2025Article
- Clinical applications of artificial intelligence and machine learning in neurocardiology: a comprehensive review.Frontiers in cardiovascular medicine · 2025Review
- Clinical research progress on pathogenesis and treatment of Patent Foramen Ovale-associated stroke.Frontiers in neurology · 2025Review
- Left Atrial Appendage Opacification on Cardiac Computed Tomography in Acute Ischemic Stroke: The Clinical Implications of Slow-Flow.Journal of the American Heart Association · 2024Article
- The relationship between atrial cardiopathy biomarkers and prognosis of patients with acute ischemic stroke after endovascular treatment.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024Article
- Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation.PloS one · 2024Article
- Comparison between left bundle branch area pacing and right ventricular pacing: ventricular electromechanical synchrony and risk of atrial high-rate episodes.Frontiers in cardiovascular medicine · 2024Article
- The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function.Journal of clinical medicine · 2023Review
- Ischemia with Nonobstructive Coronary Artery Disease and Atrial Cardiomyopathy-Two Sides of the Same Story?Life (Basel, Switzerland) · 2023Review
- Potential Embolic Sources in Embolic Stroke of Undetermined Source Patients with Patent Foramen Ovale.Cerebrovascular diseases (Basel, Switzerland) · 2023Article
- Arterial Hypertension and Its Consequences Are the Main Predictors of Embolic Stroke of Undetermined Source.Disease markers · 2023Article
- Atrial cardiomyopathy: from cell to bedside.ESC heart failure · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nearly 30% of ischemic strokes have an unknown cause, which are referred to as cryptogenic strokes (CS). Imaging studies suggest that a large proportion of these patients show features that are consistent with embolism, and thus the term embolic stroke of undetermined source (ESUS) was proposed to describe these CS patients. Atrial cardiomyopathy predisposes to thrombus formation and thus embolic stroke even in the absence of atrial fibrillation (AF). This may provide a mechanistic link with ESUS, suggesting that anticoagulant therapy may be more beneficial than antiplatelet therapy in ESUS patients with atrial cardiomyopathy. The present review discusses the concept of atrial cardiomyopathy and ESUS and the relationship between them based on the mechanisms and clinical evidence, suggests that atrial cardiomyopathy may be a potential mechanism of ESUS, and highlights a theoretical basis that supports that anticoagulant therapy may be more applicable to ESUS patients with atrial cardiomyopathy and aims to help us better understand and identify the risk of ESUS, thereby improving the management of these patients in clinical practice.
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