Evidence map›Paper›PMID 34434596›Full record

ArticleJournal of health & pollution2021

Relationship between Respiratory Morbidity and Environmental Exposure to Organochlorine Pesticides in Armenia.

Natalya S Tadevosyan, Gayane V Kirakosyan, Susanna A Muradyan, Susanna B Poghosyan, Bavakan G Khachatryan

Open access · diamondAbstract read
In one paragraph

Article in Journal of health & pollution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Natalya S TadevosyanMkhitar Heratsi Yerevan State Medical University, Yerevan, Republic of Armenia.ORCID https://orcid.org/0000-0002-4753-489X
Gayane V KirakosyanMkhitar Heratsi Yerevan State Medical University, Yerevan, Republic of Armenia.ORCID https://orcid.org/0000-0002-2612-4605
Susanna A MuradyanMkhitar Heratsi Yerevan State Medical University, Yerevan, Republic of Armenia.ORCID https://orcid.org/0000-0001-5075-9152
Susanna B PoghosyanMkhitar Heratsi Yerevan State Medical University, Yerevan, Republic of Armenia.ORCID https://orcid.org/0000-0002-5834-1102
Bavakan G KhachatryanMkhitar Heratsi Yerevan State Medical University, Yerevan, Republic of Armenia.ORCID https://orcid.org/0000-0002-1825-3300
Yerevan State Medical University · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies have investigated the effects of organochlorine pesticides (OCPs) on adverse health outcomes. However, studies addressing the link between respiratory health and OCPs are limited. Organochlorine pesticides are stable compounds and belong to the class of endocrine disrupting chemicals that represent a threat to global health.

objectivesThe aim of the present study was to examine the association between respiratory morbidity and environmental exposure to OCPs in selected regions in Armenia.

methodsThe study was carried out in Lori and Gegharkunik provinces/marzes. The prevalence rate (per 100 000 population) and the average chronological indicators (ACh) for all respiratory diseases and asthma were calculated. Concentrations of OCPs (γ-hexachlorocyclohexane (γ-HCH), dichloro-diphenyl-trichloroethane [DDT], dichlorodiphenyldichloroethylene (DDE) and dichloro-diphenyl-dichloroethane (DDD)) were determined in soil and plant product samples and the average annual total concentration (AATC) of OCPs (γ-HCH + 4,4'-DDT + 4,4'-DDE+4,4'-DDD) was calculated.

resultsThe ACI for all respiratory diseases showed a growth tendency in areas of Gegharkunik province ranging from 14.2 to 20.9% and an increase in asthma ranging from 9.4% to 174.6%. The highest levels of AATC of OCPs were found in soil sampled in Gegharkunik province: 9.48 ± 1.11 μg/kg and 8.10 ± 1.05 μg/kg and these levels differed significantly from those in Lori (p=0.01-0.0007). The AATC of OCPs in plant products from Gegharkunik was also statistically higher: 1.83±0.13 μg/kg, in comparison with that of Lori province 1.31±0.09 μg/kg (p = 0.001 - 0.0000).

conclusionsThe results indicate that the increased tendency of respiratory diseases and asthma could be related to OCP residues found in soil and plant products in Gegharkunik province. However, the role of OCPs should not be ignored. Further research is needed to study OCP contamination dynamics and clarify the role of OCPs in respiratory morbidity. COMPETING INTERESTS: The authors declare no competing financial interests.

Indexed as

environmental exposureorganochlorine pesticidespollutionrespiratory morbidity, endocrine disrupting chemicals

Identifiers

PMID34434596
PMCPMC8383794
OpenAlexW3194379135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.