Evidence map›Paper›PMID 34434554›Full record

ArticleClinical & translational immunology2021

A novel computer vision-based assessment of neutrophil chemotaxis in patients with severe infection.

Yunxi Yang, Lu Liu, Zaiwen Guo, Jiamin Huang, Linbin Li, Yiming Shao, Mingming Song, Aixiang Yang, Bingwei Sun

Abstract read
In one paragraph

Article in Clinical & translational immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. [Regulatory effects of theZhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Article
  5. [Re-understanding the physiological and pathophysiological roles of neutrophils].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022
    Article
  6. Frontiers in immunology · 2022
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunxi YangSchool of Medicine Jiangsu University Zhenjiang Jiangsu Province China.
Lu LiuSchool of Medicine Jiangsu University Zhenjiang Jiangsu Province China.
Zaiwen GuoDepartment of Burns and Plastic Surgery Affiliated Suzhou Hospital of Nanjing Medical University Suzhou Jiangsu Province China.
Jiamin HuangDepartment of Burns and Plastic Surgery Affiliated Suzhou Hospital of Nanjing Medical University Suzhou Jiangsu Province China.
Linbin LiDepartment of Burns and Plastic Surgery Affiliated Suzhou Hospital of Nanjing Medical University Suzhou Jiangsu Province China.
Yiming ShaoDepartment of Burns and Plastic Surgery Affiliated Suzhou Hospital of Nanjing Medical University Suzhou Jiangsu Province China.
Mingming SongDepartment of Burns and Plastic Surgery Affiliated Suzhou Hospital of Nanjing Medical University Suzhou Jiangsu Province China.
Aixiang YangDepartment of Intensive Care Medicine Affiliated Suzhou Hospital of Nanjing Medical University Suzhou Jiangsu Province China.
Bingwei SunDepartment of Burns and Plastic Surgery Affiliated Suzhou Hospital of Nanjing Medical University Suzhou Jiangsu Province China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the value of chemotactic function of neutrophils in patients with severe infections.

methodsA computer vision-based cellular chemotaxis analysis platform was established for the dynamic assessment of neutrophil chemotaxis. Fifty-three patients in the intensive care unit were eligible for the study. In parallel, 142 healthy volunteers were recruited to detect and establish the normal values for chemotactic function. Four chemotactic function indicators were determined-chemotaxis distance (CD), chemotaxis cell ratio (CCR), chemotaxis index (CI) and maximum speed of chemotaxis (V

resultsThe normal ranges of indicators were established as CD ≥ 1755.85 µm, CCR ≥ 3.34%, CI ≥ 39.63, V

conclusionsCD, CCR, CI and V

Indexed as

cell chemotaxis analysis platformchemotaxis function scoreinnate immune systemneutrophilSOFA score

Identifiers

PMID34434554
PMCPMC8373525

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.